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Met Kinase Inhibitor

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Formula: C28H30ClN5O4S
CAS: 658084-23-2
search Element: inhibitor kinase
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Identification

Structural Formula
Met Kinase Inhibitor
CAS:
658084-23-2
EINECS:
Molecular Formula:
C28H30ClN5O4S
MDL:
MFCD08276928
SMILES:
CC1=C(NC(=C1C(=O)N2CCN(CC2)C)C)C=C3C4=C(C=CC(=C4)S(=O)(=O)N(C)C5=CC(=CC=C5)Cl)NC3=O
Synonym:
SU 11274 ; (3z)-n-(3-chlorophenyl)-3-({3,5-dimethyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1h-pyrrol-2-yl}methylene)-n-methyl-2-oxo-2,3-dihydro-1h-indole-5-sulfonamide ; PKI-SU11274 ; N-(3-Chlorophenyl)-N-methyl-3-[[3,5-dimethyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-2-yl]methylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide ;


Description

Met Kinase Inhibitor is a pyrrole indolinone compound acting as an ATP-competitive inhibitor of Met kinase activity. Met Kinase Inhibitor shows great (>60-fold) selectivity over Flk and Ron, FGFR-1, c-Src, Cdk2, PDGFRβ, EGFR, and Tie-2 (>400-fold). Met Kinase Inhibitor demonstrated inhibitory effects on HGF/SF-stimulated cellular signaling and Med-mediated tumorigenisis.


Suppliers

Santa Cruz Biotechnology, Inc.
204801
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Hangzhou MolCore BioPharmatech Co.,Ltd.
MC106844

Prices & Availability




Data is processed


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Properties for Met Kinase Inhibitor

Molecular Weight:
568.09 g·mol−1
Density:
1.401 g/cm3
Solubility:
DMSO: 10 mg/mL at 60 °C
Physical Description:
orange powder
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Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
Xi
Hazard symbol Xi
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Alternative Distributors of [Met Kinase Inhibitor]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

Mol File:
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MSDS:
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