MDM2 Inhibitor | CAS 562823-84-1

Element: inhibitor mdm2

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C-S » Chemicals » mdm-inhibitor-PX63962

Identification

MDM2 Inhibitor

CAS:

562823-84-1

EINECS:

Molecular Formula:

C₁₅H₁₂ B I O₃

MDL:

MFCD06798340

SMILES:

B(C1=CC=C(C=C1)C(=O)C=CC2=CC=C(C=C2)I)(O)O

Synonym:

trans-4-iodo,4'-boranyl-chalcone ; mdm2 inhibitor ; 3-(4-iodo-phenyl)-1-(4'-boranyl-phenyl)-prop-2-enone ; boronic acid,b-[4-[(2e)-3-(4-iodophenyl)-1-oxo-2-propen-1-yl]phenyl]- ; boronicacid, [4-[(2e)-3-(4-iodophenyl)-1-oxo-2-propenyl]phenyl]- (9ci) ; 3-(4-iodo-phenyl)-1-(4''- boranyl-phenyl)-prop-2-enone (for r&d only)

Description

MDM2 Inhibitor is a cell-permeable boranyl-chalcone exhibiting strong binding to MDM2 and irreversibly disrupts the MDM2/p53 protein complex. MDM2 Inhibitor expresses selective toxicity towards MDM2 overexpressing human breast cancer cell lines when compared to normal breast cell lines.