JAK Inhibitor I | CAS 457081-03-7

Element: inhibitor

Page Content Identification Properties Suppliers Prices & Availability Get Quick Quote ☰

Identification Properties Suppliers Prices & Availability Get Quick Quote

C-S » Chemicals » jak-inhibitor-PX75214

Identification

JAK Inhibitor I

CAS:

457081-03-7

EINECS:

Molecular Formula:

C₁₈H₁₆FN₃O

MDL:

MFCD17019334

SMILES:

CC(C)(C)C1=NC2=C(N1)C3=C(C=C(C=C3)F)C4=C2C=CNC4=O

Synonym:

jak inhibitor i ; jak inhibitor ; cmp 6 ; 2-(1,1-dimethylethyl)-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinolin-7-one ; merck-5 ; pyridone 6 ; pyridone 6(cmp 6) ; 2-(tert-butyl)-9-fluoro-3h-benzo[h]imidazo[4,5-f]isoquinolin-7(6h)-one ; pyridone 6, >=98% ; merck-5 ,jak inhibitor i ; merk-5

Description

JAK Inhibitor I is a potent, reversible, cell-permeable, and ATP-competitive inhibitor of JAK1, JAK2, and JAK3. Primary target: murine JAK1. JAK1 (Janus kinase 1), JAK2 and JAK3 belong to the family of non-receptor janus tyrosine kinases, which regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. Immunological stimuli, such as interferons and cytokines, induce recruitment of STAT transcription factors to cytokine receptor-associated JAK1, JAK2 and JAK3.

Suppliers

Santa Cruz Biotechnology, Inc.

204021

Get Quick Quote

CAS equal suppliers

CMP 6

Chemieliva Pharmaceutical Co., Ltd.

CP175525

CMP 6

Leap Chem Co., Ltd

LC90270

merk-5

Pharmacore Co., Limited

PL138414

Merck-5

Capot Chemical Co., Ltd.

22471

Pyridone6

Huateng Pharmaceutical Co.,Ltd

91934

Pyridone 6

ShangHai Biochempartner Co., Ltd.

BCP01959

Pyridone 6

Aea.ltd

A70140

2-tert-Butyl-9-fluoro-3H-benzo[h]imidazo[4,5-f]isoquinolin-7(6H)-one

Hangzhou MolCore BioPharmatech Co.,Ltd.

MC111370

Prices & Availability

Data is processed

Properties for JAK Inhibitor I

Molecular Weight:

309.13 g·mol−1

Density:

1.329 g/cm3

Melting point:

251.66° C (Predicted)

Boiling point:

646.481 °C at 760 mmHg

Flash point:

344.78 °C

Solubility:

Soluble in DMSO (5 mg/ml).

Safety & Transport Information

coming up soon

Alternative Distributors of [JAK Inhibitor I]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Shanghai Witofly Chemical Co., Ltd.