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JAK3 Inhibitor IV

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Formula: C23H25NO.HCl
CAS: 58753-54-1
search Element: inhibitor jak3
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Identification

Structural Formula
JAK3 Inhibitor IV
CAS:
58753-54-1
EINECS:
Molecular Formula:
C23H25NO.HCl
MDL:
MFCD04974534
SMILES:
CC(C)N(CCC(=O)C1=CC2=CC=CC=C2C=C1)CC3=CC=CC=C3.Cl
Synonym:


Description

JAK3 Inhibitor IV is a potent, selective, and ATP-competitive inhibitor of JAK3 (pIC50 = 7.1). JAK3 Inhibitor IV is a weak inhibitor of JAK1 (pIC50 = 4.4) and EGF-R (pIC50 = 5.6). JAK3 Inhibitor IV undergoes a retro-Michael breakdown to another active analog, 2-naphthylvinyl ketone (JAK3 Inhibitor V) (t½ = 36 min.)


Suppliers

Santa Cruz Biotechnology, Inc.
295217
Dayang Chem (Hangzhou) Co.,Ltd.
DC15816324
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Prices & Availability




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Properties for JAK3 Inhibitor IV

Molecular Weight:
367.91 g·mol−1
Melting point:
151-154 °C (lit.)
Boiling point:
478.8 °C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (36 mg/ml).
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Alternative Distributors of [JAK3 Inhibitor IV]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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