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JAK3 Inhibitor V

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Formula: C13H10O
CAS: 4452-06-6
search Element: inhibitor jak3
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Identification

Structural Formula
JAK3 Inhibitor V
CAS:
4452-06-6
EINECS:
Molecular Formula:
C13H10O
MDL:
MFCD04974535
SMILES:
C=CC(=O)C1=CC2=CC=CC=C2C=C1
Synonym:


Description

JAK3 Inhibitor V is a potent, selective inhibitor of JAK3 (Janus tyrosine kinase 3) which binds competitively to the JAK3 ATP site. pIC50 values are 6.8, 5.0, 4.7, and < 5.0 for JAK3, EGFR, JAK1 and CDK4 respectively. JAK3 Inhibitor V inhibits STAT-5 phosphorylation and T-cell proliferation.


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Santa Cruz Biotechnology, Inc.
295218
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Properties for JAK3 Inhibitor V

Molecular Weight:
182.22 g·mol−1
Density:
1.10 g/cm3 (Predicted)
Melting point:
75.35 °C (Predicted)
Boiling point:
319.28 °C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (10 mg/ml), and ethanol (10 mg/ml).
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Safety & Transport Information

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Alternative Distributors of [JAK3 Inhibitor V]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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