16,16-Dimethyl-prostaglandin E2 | CAS 39746-25-3

Element: prostaglandin dimethyl

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Identification

16,16-Dimethyl-prostaglandin E2

CAS:

39746-25-3

EINECS:

Molecular Formula:

C₂₂H₃₆O₅

MDL:

MFCD00151141

SMILES:

CCCCC(C)(C)[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CC=C/CCCC(O)=O

Synonym:

suppliedasayellow,viscousoil ; 5-heptenoicacid,7-(2-(4,4-dimethyl-3-hydroxy-1-octenyl)-3-hydroxy-5-oxocycl ; 16,16-dimethyl prostaglandin e2 ; 15r)-13e ; 9-oxo-11alpha,15r-dihydroxy-16,16-dimethyl-prosta-5z,13e-dien-1-oic acid ; opentyl)- ; 16,16-dimethyl-pge2 ; 16,16-dimethyl dinoprostone ; 16,16-dimethylprostaglandinee2 ; 16,16-dimethyl prostaglandin e2 supplied as a yellow, viscous oil

Description

16,16-Dimethyl-prostaglandin E₂ is an antisecretory, antiulcer Prostaglandin E₂ (PGE₂) analog with potent cytoprotective activity that binds to PGDH (prostaglandin dehydrogenase or HPGD), but is resistant to metabolism, thereby inhibiting the enzyme. This enhanced resistance to metabolism imparts a higher duration of activity than Prostaglandin E₂, but the methylations do not severely affect the binding affinity for all four EP receptors (EP1,2,3, and 4). PGE₂ is the most physiologically abundant eiconasoid regulating many biological functions and since this product has nearly identical binding affinities, it also has numerous and similar physiological functions. 16,16-Dimethyl-prostaglandin E₂ is an inhibitor of PGDH and an activator of EP₂.

Suppliers

Santa Cruz Biotechnology, Inc.

201240

Santa Cruz Biotechnology, Inc.

sc-201240

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Prices & Availability

Data is processed

Properties for 16,16-Dimethyl-prostaglandin E2

Molecular Weight:

380.52 g·mol−1

Boiling point:

57° C

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36 - Irritating to eyes
R36/37/38 - Irritating to eyes, respiratory system and skin
R66 - Repeated exposure may cause skin dryness or cracking
R67 - Vapours may cause drowsiness and dizziness

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

F, Xn, Xi

Storage temperature :

-20°C

RID/ADR certification :

UN 1231 3 / PG 2

Alternative Distributors of [16,16-Dimethyl-prostaglandin E2]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences