Prostaglandin E2 methyl ester | CAS 31753-17-0

Element: prostaglandin methyl ester

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Identification

Prostaglandin E2 methyl ester

CAS:

31753-17-0

EINECS:

Molecular Formula:

C₂₁H₃₄ O₅

MDL:

SMILES:

CCCCCC(O)/C=C/[C@H]1C(O)CC(=O)C1C/C=CCCCC(=O)OC

Synonym:

5-Heptenoicacid, 7-[3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-, methyl ester,stereoisomer (8CI) ; (-)-Prostaglandin E2 methyl ester ; PGE2 methyl ester ; Prostaglandin E2 methyl ester ; Prosta-5,13-dien-1-oicacid, 11,15-dihydroxy-9-oxo-, methyl ester, (5Z,11a,13E,15S)-

Description

Prostaglandin E₂ methyl ester is an analog of PGE₂ with enhanced lipid solubility, that has been suggested to play a role in rapid-eye-movement sleep regulation. PGE₂ is the most physiologically abundant eicosanoid, which is produced predominantly from arachidonic acid by COX and PGE₂, and exists at some level in nearly all cell types. PGE₂ acts on four different receptors termed EP₁ through EP₄ yielding an astounding array of biological effects; the use of these prostaglandin analogues is integral for structure-activity studies used in the deconvolution of these complex biochemical pathways.