ALK5 Inhibitor II | CAS 446859-33-2

Element: inhibitor alk5

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C-S » Chemicals » alk-inhibitor-PX66983

Identification

ALK5 Inhibitor II

CAS:

446859-33-2

EINECS:

Molecular Formula:

C₁₇H₁₃N₅

MDL:

MFCD09037561

SMILES:

CC1=CC=CC(=N1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4

Synonym:

repsox (sjn 2511) ; e616452 ; alk5 inhibitor ii ; repsox ; 1,5-naphthyridine, 2-[3-(6-methyl-2-pyridinyl)-1h-pyrazol-4-yl]- ; e 616452 ; e-616452 ; alk5 inhibitor i ; alk 5 inhibitor ii ; repsox(e-616452 ; sjn 2511 ; repsox, >=98%

Description

ALK5 Inhibitor II is a cell permeable, potent, selective and ATP-competitive inhibitor of TGF-β RI kinase (IC₅₀=23nM, 4nM and 18nM for binding, auto-phosphorylation and cellular assay in HepG2 cells of TGF-β RI kinase, respectively). TGF β RI (ALK5) Inhibitor II affects a panel of 9 closely related kinases including p38 MAPK (IC₅₀ >16μM), minimally.

Suppliers

Amadis Chemical Company Limited

ACCL15817905

Santa Cruz Biotechnology, Inc.

221234

Dayang Chem (Hangzhou) Co.,Ltd.

DC15816324

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CAS equal suppliers

RepSox

Leap Chem Co., Ltd

LC108324

RepSox

Hangzhou Yuhao Chemical Technology Co., Ltd

ZW0008

RepSox

ShangHai Biochempartner Co., Ltd.

BCP04103

RepSox

Excenen Pharmatech Co., Ltd.

EX-A2879

RepSox

CSNpharm, Inc.

CSN12299

RepSox

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI4141656

SJN 2511

Aea.ltd

A56112

ALK5 INHIBITOR

Capot Chemical Co., Ltd.

24163

Alk 5 Inhibitor II

Hangzhou Yuhao Chemical Technology Co., Ltd

RT8351

Alk5 inhibitor II hydrochloride

BOC Sciences

BS14884464

2-(3-(6-METHYLPYRIDIN-2-YL)-1H-PYRAZOL-4-YL)-1,5-NAPHTHYRIDINE

Hangzhou J&H Chemical Co., Ltd.

HJC1729869192

2-(3-(6-METHYLPYRIDIN-2-YL)-1H-PYRAZOL-4-YL)-1,5-NAPHTHYRIDINE

Skyrun Industrial Co., Ltd.

SI1506645198

1,5-Naphthyridine, 2-[3-(6-methyl-2-pyridinyl)-1h-pyrazol-4-yl]-

Angene International Limited

AGN-PC-0OAHA7

Prices & Availability

Data is processed

Properties for ALK5 Inhibitor II

Molecular Weight:

287.31862 g·mol−1

Density:

1.297 g/cm3

Melting point:

191° C

Boiling point:

501.911 °C at 760 mmHg

Flash point:

230.461 °C

Solubility:

Soluble in DMSO (100 mM), methanol (5 mg/ml), and ethanol (50 mM).

Safety & Transport Information

Risk Codes:

R25 - Toxic if swallowed

Safety Codes:

S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Symbols:

Storage temperature :

Store at +4 °C

RID/ADR certification :

UN 2811

Alternative Distributors of [ALK5 Inhibitor II]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

ShangHai Biochempartner Co., Ltd. | Shanghai Witofly Chemical Co., Ltd.