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Leptomycin A

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Formula: C32H46O6
CAS: 87081-36-5
search Element: leptomycin
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Identification

Structural Formula
Leptomycin A
CAS:
87081-36-5
EINECS:
Molecular Formula:
C32H46O6
MDL:
MFCD01711669
SMILES:
CC1C=CC(=O)OC1/C=C/C(=C/C(C)C/C=C/C(=C/C(C)C(=O)C(C)C(C(C)C/C(=C/C(=O)O)/C)O)/C)/C
Synonym:
ats 1287a, pd 118607, jildamycin ; 19-(3,6-dihydro-3-methyl-6-oxo-2h-pyran-2-yl)-3,5,7,9,11,15,17-heptamethyl-6-hydroxy-8-oxo-2,10,12,16,18-nonadecapentaenoic acid ; antibiotic pd-118607 ; nsc 369326 ; pd-118607 ; 2,10,12,16,18-nonadecapentaenoicacid,19-[(2s,3s)-3,6-dihydro-3-methyl-6-oxo-2h-pyran-2-yl]-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-,(2e,5s,6r,7s,9r,10e,12e,15r,16z,18e)- ; 19-(3,6-dihydro-3-methyl-6-oxo-2h-pyran-2-yl)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-2,10,12,16,18-nonadecapentaenoic acid ; antibiotic ats-1287a


Description

Leptomycin A is an antifungal antibiotic that acts as an inhibitor of nuclear export by interacting with CRM1/exportin-1. Inhibits nucleo-cytoplasmic translocation of molecules such as the HIV-1 Rev protein and Rev-dependent export of mRNA.


Suppliers

Aea.ltd
A168336
+
Leap Chem Co., Ltd
LC4321296
+
Santa Cruz Biotechnology, Inc.
203102
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Prices & Availability




Data is processed


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Properties for Leptomycin A

Molecular Weight:
526.709 g·mol−1
Boiling point:
78° C
Solubility:
Soluble in methanol or 100% ethanol.
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Safety & Transport Information

Risk Codes:
R11 - Highly flammable
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
F, T
Hazard symbol T Hazard symbol F
Storage temperature :
?20 °C
RID/ADR certification :
UN 1230 3 / PG 2
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Alternative Distributors of [Leptomycin A]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Shanghai Witofly Chemical Co., Ltd. | Clearsynth Canada INC.

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Downloads

Mol File:
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MSDS:
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