12(S)-HETE-d8 | CAS 84807-90-9 | Chemical-Suppliers

Element: hete

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C-S » Chemicals » hete-PX75859

Identification

12(S)-HETE-d8

CAS:

84807-90-9

EINECS:

Molecular Formula:

C₂₀H₂₄ D₈ O₃

MDL:

MFCD00084827

SMILES:

[2H]/C(=C([2H])/C[C@@]([2H])(/C(=C/C(=C(/[2H])C/C(=C(/[2H])CCCC(=O)O)/[2H])/[2H])/[2H])O)/CCCCC

Synonym:

12(s)-hete-d8 ; 12s-hydroxy-5z,8z,10e,14z-eicosatetraenoic acid-5,6,8,9,11,12,14,15-d8 acid ; 5,8,10,14-eicosatetraenoic-5,6,8,9,11,12,14,15-d8acid, 12-hydroxy-, (5z,8z,10e,12s,14z)- ; 5,8,10,14-eicosatetraenoic-5,6,8,9,11,12,14,15-d8acid, 12-hydroxy-, [s-(e,z,z,z)]-

Description

12(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. It is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS). 12(S)-HETE is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1μM.