8(S)-HETE | CAS 98462-03-4 | Chemical-Suppliers

Element: hete

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C-S » Chemicals » hete-PX79368

Identification

8(S)-HETE

CAS:

98462-03-4

EINECS:

Molecular Formula:

C₂₀H₃₂O₃

MDL:

MFCD00063584

SMILES:

CCCCC/C=CC/C=CC=C[C@H](C/C=CCCCC(=O)O)O

Synonym:

8(s)-hete ; 8(s)-hydroxyeicosa-5z,9e,11z,14z-tetraenoic acid ; (5z,8s,9e,11z,14z)-8-hydroxyicosa-5,9,11,14-tetraenoic acid ; 8-hydroxy-[s-(e,z,z,z)]-5,9,11,14-eicosatetraenoic acid ; 8(s)-hete lipid maps ms standard ; 8(s)-hydroxy-(5z,9e,11z,14z)-eicosatetraenoic acid

Description

8(S)-HETE is a polyunsaturated fatty acid chemotactic for neutrophils and an intermediate in the synthesis of the family of eicosanoids known as leukotrienes. The compound has been observed to be biosynthesized in human neutrophils, phorbol ester-treated mouse epidermis and by hepatic microsomal cytochrome P-4503. 8(S)-HETE has been observed to regulate epithelial cell migration in the rat cornea. The compound has also been recognized as the key component of arachidonic acid in corneal wound healing. Evidence demonstrates 8(S)-HETE activates PPARα and PKC.

Suppliers

Santa Cruz Biotechnology, Inc.

200940

Santa Cruz Biotechnology, Inc.

sc-200940

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Prices & Availability

Data is processed

Properties for 8(S)-HETE

Molecular Weight:

320.47 g·mol−1

Boiling point:

78° C

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

F, Xi