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FTI-276 trifluoroacetate salt

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Formula: C21H27 N3 O3 S2
CAS: 170006-72-1

Identification

Structural Formula
FTI-276 trifluoroacetate salt
CAS:
170006-72-1
EINECS:
Molecular Formula:
C21H27 N3 O3 S2
MDL:
SMILES:
CSCC[C@@H](C(=O)O)NC(=O)C1=C(C=C(C=C1)NC[C@H](CS)N)C2=CC=CC=C2.C(=O)(C(F)(F)F)O
Synonym:
fti-276 ; n-[2-phenyl-4-n[2(r)-amino-3-mercaptopropylamino benzoyl]-methionine, tfa ; fti-276 trifluoroacetate salt ; l-methionine,n-[[5-[(2-amino-3-mercaptopropyl)amino][1,1'-biphenyl]-2-yl]carbonyl]-, (r)- ; fti 276 ; n-[4-[2-(r)-amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine trifluoroacetate salt ; l-methionine,n-[[5-[[(2r)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-


Description

FTI-276 trifluoroacetate salt is a highly potent RasCAAX peptidomimetic which antagonizes both H and K-Ras oncogenic signaling. This compound inhibits farnesyltransferase (Ftase) in vitro with an IC50 of 500 pM. RasCAAX as an anti-cancer agent.


Suppliers

Santa Cruz Biotechnology, Inc.
215057
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Properties for FTI-276 trifluoroacetate salt

Molecular Weight:
433.59 g·mol−1
Solubility:
H2O: >5 mg/mL, soluble
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Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
-20°C
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Alternative Distributors of [FTI-276 trifluoroacetate salt]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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MSDS:
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