PI 3-Kβ Inhibitor VI, TGX-221 | CAS 663619-89-4

Element: inhibitor beta

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Identification

PI 3-Kβ Inhibitor VI, TGX-221

CAS:

663619-89-4

EINECS:

Molecular Formula:

C₂₁H₂₄N₄O₂

MDL:

MFCD11113209

SMILES:

CC1=CN2C(=O)C=C(N=C2C(=C1)C(C)NC3=CC=CC=C3)N4CCOCC4

Synonym:

7-methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]-4h-pyrido[1,2-a]pyrimidin-4-one ; 4h-pyrido[1,2-a]pyrimidin-4-one, 7-methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]- ; (+/-)-7-methyl-2-(morpholin-4-yl)-9-(1-phenylaminoethyl)pyrido[1,2-a]pyrimidin-4-one tgx 221 ; (+/-)-7-methyl-2-(morpholin-4-yl)-9-(1-phenylaminoethyl)pyrido[1,2-a]pyrimidin-4-one ; tgx 221 ; pi 3-kβ inhibitor vi, tgx-221 ; tgx 221 (+/-)-7-methyl-2-(morpholin-4-yl)-9-(1-phenylaminoethyl)pyrido[1,2-a]pyrimidin-4-one

Description

PI 3-Kβ Inhibitor VI, TGX-221 is a cell-permeable morpholino-pyrimidinone compound that acts as a reversible, ATP-competitive, selective, and highly potent inhibitor of PI 3-kinase β (IC₅₀ = 0.005, 0.1, 5, and ≥3.5 µM for -β, -δ, -α and -γ isoforms, respectively) with little activity against a panel of 15 commonly studied protein kinases even at concentrations as high as 10.0 µM. PI 3-Kβ Inhibitor VI, TGX-221 is an excellent tool for studying p110b-dependent responses in cells in vitro.

Suppliers

Santa Cruz Biotechnology, Inc.

203190

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CAS equal suppliers

TGX221

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Capot Chemical Co., Ltd.

22489

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BOC Sciences

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Aea.ltd

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Excenen Pharmatech Co., Ltd.

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CSNpharm, Inc.

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PI 3-Kbeta Inhibitor VI, TGX-221

Santa Cruz Biotechnology, Inc.

sc-203190

7-Methyl-2-(morpholin-4-yl)-9-[1-(phenylamino)ethyl]pyrido[1,2-a]pyrimidin-4-one

Gihi Chemicals Co., Limited

GCL28080112320

4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, 7-METHYL-2-(4-MORPHOLINYL)-9-[1-(PHENYLAMINO)ETHYL]-

Chemieliva Pharmaceutical Co., Ltd.

CP35700107100

Prices & Availability

Data is processed

Properties for PI 3-Kβ Inhibitor VI, TGX-221

Molecular Weight:

363.4 g·mol−1

Safety & Transport Information

coming up soon

Alternative Distributors of [PI 3-Kβ Inhibitor VI, TGX-221]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Suzhou Rovathin Pharmatech Co., Ltd | BOC Sciences