Physostigmine | CAS 57-47-6 | Chemical-Suppliers

Element: physostigmine

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C-S » Chemicals » physostigmine-PX67646

Identification

Physostigmine

CAS:

57-47-6

EINECS:

200-332-8

Molecular Formula:

C₁₅H₂₁N₃O₂

MDL:

MFCD00151090

SMILES:

C[C@@]12CCN([C@@H]1N(C3=C2C=C(C=C3)OC(=O)NC)C)C

Synonym:

physostol ; cogmine ; nih10421 ; synapton ; ezerin ; mcv4484 ; cs 58525 ; cs58525 ; erserine ; eserine

Description

Physostigmine is an alkaloid originally derived from the Calabar bean (Physostigma venenosum) and noted to act as a potent and reversible inhibitor of cholinesterase. Physostigmine is also reported to form a slowly degrading carbamylated enzyme complex with AChE (acetylcholinesterase). This compound has been used as a positive control in a study investigating acetylcholinesterase inhibitors for potential antihelminthic drug targets. Additionally, this parasympathomimetic compound is reported to cross the blood-brain barrier.

Suppliers

Finetech Industry Limited

FIL3251300

Santa Cruz Biotechnology, Inc.

202764

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Prices & Availability

Data is processed

Properties for Physostigmine

Molecular Weight:

275.35 g·mol−1

Density:

1.166 ±0.06 g/cm3 (20 °C 760 Torr)

Melting point:

102-104 °C(lit.)

Boiling point:

~393.5° C at 760 mmHg (Predicted)

Solubility:

Soluble in water (1:75), alcohol (1:10), chloroform (1:1), ether (1:30), and DMSO.

Safety & Transport Information

Risk Codes:

R26/28 - Very toxic by inhalation and if swallowed

Safety Codes:

S23 - Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer)
S25 - Avoid contact with eyes
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Classes:

6.1(a)

Hazard Symbols:

T+

Storage temperature :

2-8°C

RID/ADR certification :

UN 1544 6.1 / PG 1

Alternative Distributors of [Physostigmine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Advance Scientific & Chemical, Inc. | ABCR GmbH & Co. KG | Clearsynth Canada INC.