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Physostigmine hemisulfate

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Formula: (C15H21N3O2)2.H2SO4
CAS: 64-47-1

Identification

Structural Formula
Physostigmine hemisulfate
CAS:
64-47-1
EINECS:
200-585-4
Molecular Formula:
(C15H21N3O2)2.H2SO4
MDL:
MFCD06795853
SMILES:
C[C@@]12CCN([C@@H]1N(C3=C2C=C(C=C3)OC(=O)NC)C)C.C[C@@]12CCN([C@@H]1N(C3=C2C=C(C=C3)OC(=O)NC)C)C.OS(=O)(=O)O
Synonym:
physostigmine sulfate ; eserinesulphate ; physosotigminesulphate ; physostigminsulfat ; physostigmineso4 ; eserine hemisulfate salt ; eserine hemisulfate ; physostigminesulphate ; physostigmine hemisulfate ; eserine sulfate


Description

Physostigmine hemisulfate is a derivative of Physostigmine. Physostigmine is an alkaloid originally derived from the Calabar bean (Physostigma venenosum) and noted to act as a potent and reversible inhibitor of AchE (acetylcholinesterase). Physostigmine is also reported to form a slowly degrading carbamylated enzyme complex with AChE (acetylcholinesterase). This compound has been used as a positive control in a study investigating AChE (acetylcholinesterase) inhibitors for potential antihelminthic drug targets. Additionally, this parasympathomimetic compound is reported to cross the blood-brain barrier in a research study.


Suppliers

Santa Cruz Biotechnology, Inc.
203661
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Properties for Physostigmine hemisulfate

Molecular Weight:
648.77 g·mol−1
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Safety & Transport Information

Risk Codes:
R26/28 - Very toxic by inhalation and if swallowed
Safety Codes:
S25 - Avoid contact with eyes
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
6.1(a)
Hazard Symbols:
T+
Hazard symbol T+
Storage temperature :
2-8°C
RID/ADR certification :
UN 2811 6.1 / PG 1
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Alternative Distributors of [Physostigmine hemisulfate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | Pfaltz & Bauer, Inc. | Salsbury Chemicals, Inc., | Clearsynth Canada INC.

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MSDS:
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