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Physostigmine salicylate

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Formula: C15H21N3O2•C7H6O3
CAS: 57-64-7
search Element: physostigmine salicylate
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Identification

Structural Formula
Physostigmine salicylate
CAS:
57-64-7
EINECS:
200-343-8
Molecular Formula:
C15H21N3O2•C7H6O3
MDL:
SMILES:
C[C@@]12CCN(C1N(C3=C2C=C(C=C3)OC(=O)NC)C)C.C1=CC=C(C(=C1)C(=O)O)O
Synonym:
physostigminsalicylat ; ar-44 ; tl-1380 ; eserine monosalicylate ; eserinesalicylatesalt ; eserine salicylate(rg) ; eserine salicylate salt ; physostigmine salicylate ; physostolsalicylate ; isopto eserine ; eserine salicylate ; physostigmine salicylate (1:1) ; physostigminesalicylate


Description

Physostigmine salicylate is a derivative of Physostigmine. Physostigmine is an alkaloid originally derived from the Calabar bean (Physostigma venenosum) and noted to act as a potent and reversible inhibitor of cholinesterase. Physostigmine is also reported to form a slowly degrading carbamylated enzyme complex with acetylcholinesterase (AChE). This compound has been used as a positive control in a study investigating acetylcholinesterase inhibitors for potential antihelminthic drug targets. Additionally, this parasympathomimetic compound is reported to cross the blood-brain barrier.


Suppliers

Autech Industry Co.,Limited
AIC12965184
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Aozeal Certified Standards (AOCS), Inc.
P0220.00
+
Lori Industry Co., Ltd
LI10563168
+
Refine Chemical Co.,Ltd.
RCC11524608
+
R&D Scientific Inc.
RS9122736
+
OPQ Chemical Co., Ltd
OC10083024
+
Nantong Xindao Biotech Ltd
NXB12484992
+
Xiamen Equation Chemical Co.,Ltd
XECC15367680
+
Hangzhou Keying Chem Co., Ltd.
HKC14405760
+
Sigma-Aldrich International GmbH
SI15364608
+
BOC Sciences
BS5761728
+
Amadis Chemical Company Limited
ACCL14887440
+
Santa Cruz Biotechnology, Inc.
252784
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KCIS7923960

Prices & Availability




Data is processed


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Properties for Physostigmine salicylate

Molecular Weight:
413.52 g·mol−1
Melting point:
181-183 °C
Boiling point:
393.5 °C at 760 mmHg
Flash point:
191.8 °C
Solubility:
Sparingly soluble in water; soluble in ethanol (~750 g/l) TS; slightly soluble in ether R.
Physical Description:
colourless crystals; odourless.
Transport Information:
UN 1544 6
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Safety & Transport Information

Risk Codes:
R26/28 - Very toxic by inhalation and if swallowed
Safety Codes:
S25 - Avoid contact with eyes
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
6.1(a)
Hazard Symbols:
T+
Hazard symbol T+
RID/ADR certification :
UN 1544 6.1 / PG 1
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Alternative Distributors of [Physostigmine salicylate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | ABCR GmbH & Co. KG | TCI Europe NV

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Downloads

Mol File:
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MSDS:
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