Chemical-Suppliers Chemical-Suppliers

MIF Antagonist, ISO-1

×
Formula: C12H13NO4
CAS: 478336-92-4
search Element: antagonist
Page Content Identification Properties Suppliers Prices & Availability Get Quick Quote ☰

Identification

Structural Formula
MIF Antagonist, ISO-1
CAS:
478336-92-4
EINECS:
Molecular Formula:
C12H13NO4
MDL:
SMILES:
COC(=O)CC1CC(=C2C=CC(=O)C=C2)NO1
Synonym:
5-Isoxazoleacetic acid, 4,5-dihydro-3-(4-hydroxyphenyl)-, methyl ester


Description

MIF Antagonist, ISO-1 is a cell-permeable isoxazoline compound that displays anti-inflammatory properties. MIF Antagonist, ISO-1 inhibits MIF dopachrome tautomerase activity by binding to its catalytic active site (IC50 = 7 µM for D-dopachrome tautomerase) and suppresses the production of TNFα, PGE2 and COX-2 in human monocytes and arachidonic acid in RAW 264.7 macrophages. MIF Antagonist, ISO-1 has been shown to exhibit antidiabetogenic properties in immunoinflammatory diabetic mouse model.


Suppliers

Santa Cruz Biotechnology, Inc.
204807
Get Quick Quote

CAS equal suppliers

ISO-1
Excenen Pharmatech Co., Ltd.
EX-A2475
ISO-1
CSNpharm, Inc.
CSN13563
ISO-1
Aea.ltd
A3570
5-Isoxazoleacetic acid, 4,5-dihydro-3-(4-hydroxyphenyl)-, methyl ester
Angene International Limited
AGN-PC-0OAPUO

Prices & Availability




Data is processed


x

Properties for MIF Antagonist, ISO-1

Molecular Weight:
235.24 g·mol−1
Density:
~1.3 g/cm3 (Predicted)
Melting point:
133.69° C (Predicted)
Boiling point:
~337.6° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO.
x

Safety & Transport Information

coming up soon
x

Alternative Distributors of [MIF Antagonist, ISO-1]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
x

Downloads

Mol File:
-/-
MSDS:
-/-




View related products













▲
▲