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IL-1R Antagonist

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Formula: C18H26N2O2
CAS: 566914-00-9
search Element: antagonist
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Identification

Structural Formula
IL-1R Antagonist
CAS:
566914-00-9
EINECS:
Molecular Formula:
C18H26N2O2
MDL:
MFCD06411423
SMILES:
CC(C)[C@@H](C(=O)N1CCCC1)NC(=O)CCC2=CC=CC=C2
Synonym:


Description

IL-1R Antagonist is a cell-permeable, end protected L-valyl derivative modeled on the MyD88-binding sequence of the TIR domain BB-loop of IL-1RI. It specifically inhibits TIR domain-mediated MyD88/IL1-RI interaction without affecting TLR4/MyD88 interaction. Has shown to activate the MAP kinase signaling cascades in murine lymphocytes and EL4 thymoma cells in vitro.


Suppliers

Amadis Chemical Company Limited
ACCL14887440
+
Santa Cruz Biotechnology, Inc.
221747
Dayang Chem (Hangzhou) Co.,Ltd.
DC14885952
+
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Prices & Availability




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Properties for IL-1R Antagonist

Molecular Weight:
302.41 g·mol−1
Density:
1.09 g/mL (Predicted)
Melting point:
198.64° C (Predicted)
Boiling point:
527.16° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (10 mg/ml), and ethanol.
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Safety & Transport Information

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Alternative Distributors of [IL-1R Antagonist]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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MSDS:
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