13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is a metabolite of PGE2 biosynthesized by the enzymes 15-hydroxy PGDH and 15-oxo-PG δ13-reductase. This compound accumulates to detectable levels, and then undergoes further metabolism and chemical decomposition, giving it a relatively short half-life (~ 9 minutes), but that is longer than PGE2 (~ 2 minutes), allowing this compound to build up to appreciable levels during PGE2 expression. Receptor binding studies indicate that although metabolites of prostaglandins typically bind to EP receptors with lower affinity, they might still play an important role in these biochemical pathways.
Properties for 13,14-dihydro-15-keto Prostaglandin E2
Molecular Weight:
352.47 g·mol−1
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Safety & Transport Information
Risk Codes:
R11 - Highly flammable R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed R36 - Irritating to eyes R36/37/38 - Irritating to eyes, respiratory system and skin R66 - Repeated exposure may cause skin dryness or cracking R67 - Vapours may cause drowsiness and dizziness
Safety Codes:
S16 - Keep away from sources of ignition - No smoking S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice S36 - Wear suitable protective clothing
Hazard Symbols:
F, Xn, Xi
Storage temperature :
-20°C
RID/ADR certification :
UN 1231 3 / PG 2
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Alternative Distributors of [13,14-dihydro-15-keto Prostaglandin E2]
Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.