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Bafilomycin B1

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Formula: C44H65NO13
CAS: 88899-56-3
search Element: bafilomycin
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Identification

Structural Formula
Bafilomycin B1
CAS:
88899-56-3
EINECS:
Molecular Formula:
C44H65NO13
MDL:
MFCD00214150
SMILES:
C[C@H]1C/C(=CC=C/[C@@H](C(OC(=O)/C(=CC(=C/[C@H]([C@H]1O)C)C)/OC)[C@@H](C)[C@H]([C@H](C)[C@]2(C[C@H]([C@@H]([C@H](O2)C(C)C)C)OC(=O)/C=C/C(=O)NC3=C(CCC3=O)O)O)O)OC)/C
Synonym:
bafilomycin b1from streptomyces sp. ; ino)carbonyl)-2-methoxy-24-methyl- ; hygrolidin,37-decarboxy-2-demethyl-37-(((2-hydroxy-5-oxo-1-cyclopenten-1-yl)am ; bafilomycin b1 ; bafilomycin b1 monohydrate from strepto- myces species ; bafilomycinb1fromstreptomycesgriseus ; 37-de(carboxy)-2-demethyl-37-[[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]carbonyl]-2-methoxy-24-methylhygrolidin


Description

Bafilomycin B1, a plecomacrolide originally found to be produced by different Streptomyces species, has been shown to display activity against gram-positive bacteria and fungi. This compound is shown to be a potent and selective inhibitor of all V-ATPases. Studies have demonstrated that Bafilomycin B1 inhibits the osteoclastic proton pump in vitro. In addition, this compound has displayed a capacity to have concentration-dependent effects on neuronal cell viability. Bafilomycin B1 may also promote the accumulation of autophagic vacuoles and trigger Bax-dependent apoptosis.


Suppliers

Iris Biotech GmbH
LS-1082.0000
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Santa Cruz Biotechnology, Inc.
202072
Dayang Chem (Hangzhou) Co.,Ltd.
DC8683472
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CAS equal suppliers

Setamycin
Leap Chem Co., Ltd
LC162486
Bafilomycin B1, 95%
Iris Biotech GmbH
LS-1082

Prices & Availability




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Properties for Bafilomycin B1

Molecular Weight:
815.99 g·mol−1
Density:
1.22 g/cm3 (Predicted)
Boiling point:
939.43° C at 760 mmHg (Predicted)
Solubility:
Soluble in methanol (5 mg/ml ), DMSO (5 mg/ml ), and acetone. Insoluble in water.
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Safety & Transport Information

Risk Codes:
R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed
Safety Codes:
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
T+
Hazard symbol T+
Storage temperature :
-20°C
RID/ADR certification :
UN 3462 6.1 / PG 1
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Alternative Distributors of [Bafilomycin B1]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Cfm Oskar Tropitzsch GmbH | BOC Sciences | Clearsynth Canada INC.

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Downloads

Mol File:
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MSDS:
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