Valproic Acid | CAS 99-66-1 | Chemical-Suppliers

Element: valproic acid

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C-S » Chemicals » valproic-acid-PX66823

Identification

Valproic Acid

CAS:

99-66-1

EINECS:

202-777-3

Molecular Formula:

C₈H₁₆O₂

MDL:

MFCD00002672

SMILES:

CCCC(CCC)C(O)=O

Synonym:

ergenyl ; convulex ; 44089 ; depakine ; depakote ; valproic ; epilim ; depakene ; mylproin ; vpa

Description

Valproic Acid is a branched chain, fatty acid which is reported to potentially enhance central GABAergic neurotransmission and inhibit Na⁺ channels. Currently, the various molecular mechanisms of action of Valproic Acid have not been completely elucidated. Valproic Acid has been reported to be a potent inhibitor of histone deacetylases (HDACs) in vitro. Valproic Acid is also noted to relieve HDAC-dependent transcriptional repression and causes the hyperacetylation of histones in cultured cells. Additionally, Valproic Acid is reported to activate Wnt-dependent gene expression and to mimic trichostatin A in the inhibition of histone deacetylase.

Suppliers

Aozeal Certified Standards (AOCS), Inc.

V0008.00

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI17947176

Shandong SanYoung Industry Co., Ltd

SSI9103640

Ambeed, Inc.

A143794

DuPont Nutrition Biosciences ApS

DNBA8324160

Austin Chemical Company, Inc.

ACC7543016

Sancai Industry Co.,Ltd.

SIC6242496

CSNpharm, Inc.

CSN13138

Sigma-Aldrich International GmbH

SI8322496

Carbone Scientific Co., Ltd.

CS7282184

AK Scientific, Inc.

AS4941482

Xingrui Industry Co., Limited

XIL7543016

Amadis Chemical Company Limited

ACCL8064030

Santa Cruz Biotechnology, Inc.

213144

Dayang Chem (Hangzhou) Co.,Ltd.

DC8063224

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Prices & Availability

Data is processed

Properties for Valproic Acid

Molecular Weight:

144.21 g·mol−1

Density:

0.92

Boiling point:

220 °C(lit.)

Flash point:

232 ºF

Solubility:

H₂O: slightly soluble

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R22 - Harmful if swallowed
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S7 - Keep container tightly closed

Hazard Classes:

Hazard Symbols:

Xn, T, F

Storage temperature :

2-8°C

RID/ADR certification :

UN 1230 3 / PG 2

Alternative Distributors of [Valproic Acid]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified