TXB2 (Thromboxane B2) | CAS 54397-85-2

Element: thromboxane txb2

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C-S » Chemicals » txb-thromboxane-PX78764

Identification

TXB2 (Thromboxane B2)

CAS:

54397-85-2

EINECS:

Molecular Formula:

C₂₀H₃₄O₆

MDL:

MFCD00135258

SMILES:

CCCCCC(C=CC1C(C(CC(O1)O)O)CC=CCCCC(=O)O)O

Synonym:

thromboxane b2 lipid maps ms standard ; 9alpha,11,15s-trihydroxythromba-5z,13e-dien-1-oic acid ; 5-heptenoic acid,7-[(2r,3s,4s)-tetrahydro-4,6-dihydroxy-2-[(1e,3s)-3-hydroxy-1-octen-1-yl]-2h-pyran-3-yl]-,(5z)- ; thromboxane b2 ; txb2 (thromboxane b2) ; 8-(1-hydroxy-3-oxopropyl)-9,12-dihydroxy-5,10-heptadecadienoic acid hemiacetal ; (5z,9α,13e,15s)-9,11,15-trihydroxythromboxa-5,13-diene-1-oic acid ; (5z,9α,11rs,13e,15s)-9,11,15-trihydroxythromboxa-5,13-dien-1-oic acid ; (5z,13e,15s)-9α,11,15-trihydroxythromboxa-5,13-dien-1-oic acid ; 5-heptenoicacid, 7-[(2r,3s,4s)-tetrahydro-4,6-dihydroxy-2-[(1e,3s)-3-hydroxy-1-octenyl]-2h-pyran-3-yl]-,(5z)- (9ci) ; thromboxane b2 eia ; (5z,9α,13e,15s)9,11,15-trihydroxythromboxa-5,13-dien-1-oic acid ; thromboxa-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5z,9α,13e,15s)- ; txb2

Description

TXB2 (Thromboxane B2) is a stable metabolite of thromboxane A2 in platelets which may be released during anaphylaxis. Reportedly possesses chemotactic properties. Often used to measure arachidonic acid metabolism. It is a prostaglandin derivative that is released during anaphylaxis, which induces arterial contraction and platelet aggregation by stimulating TP-α receptors.

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Data is processed

Properties for TXB2 (Thromboxane B2)

Molecular Weight:

370.48 g·mol−1

Density:

1.171 g/cm3

Melting point:

95-96° C

Boiling point:

582.5 °C at 760 mmHg

Flash point:

199.7 °C

Solubility:

Soluble in ethanol (~100 mg/ml), ethyl acetate, PBS pH7.2 (~100 µg/ml), and methyl acetate (~10 mg/ml). Insoluble in water.

Safety & Transport Information

Risk Codes:

R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R32 - Contact with acids liberates very toxic gas
R34 - Causes burns
R5 - Heating may cause an explosion
R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment
R63 - Possible risk of harm to the unborn child

Safety Codes:

S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Symbols:

Xn, T