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Carbocyclic Thromboxane A2

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Formula: C22H36O3
CAS: 74034-56-3
search Element: carbocyclic thromboxane
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Identification

Structural Formula
Carbocyclic Thromboxane A2
CAS:
74034-56-3
EINECS:
Molecular Formula:
C22H36O3
MDL:
SMILES:
CCCCCC(O)/C=C/[C@H]1CC2CC(C2)C1C/C=CCCCC(=O)O
Synonym:
(+/-)carbocyclic thromboxane ; cta2 ; 9alpha,11alpha-methylene-15s-hydroxy-11a-deoxy-11a-methylene-thromba-5z,13e-dien-1-oic acid ; carbocyclic thromboxane a2 ; carbocyclic txa2 ; (z)-7-[(2s)-3β-[(1e,3s)-3-hydroxy-1-octenyl]bicyclo[3.1.1]heptan-2α-yl]-5-heptenoic acid


Description

Carbocyclic Thromboxane A2(CTA2) is a stable analog of TXA2 which acts as a potent coronary vasoconstrictor at low concentrations. Unlike other vascular TP receptor agonists, CTA2 is a potent inhibitor of prostanoid-induced platelet aggregation, specifically arachidonic acid-induced aggregation (IC50 = 4-5 µM). CTA2 also exhibits dose-dependent and selective inhibition of TXB2 synthesis in rabbit platelets at concentrations between 1 and 100 µM.


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Santa Cruz Biotechnology, Inc.
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Properties for Carbocyclic Thromboxane A2

Molecular Weight:
348.52 g·mol−1
Boiling point:
78° C
Solubility:
Soluble in water (>0.1 mg/ml at 25.0° C), DMSO (~25 mg/ml), DMF (~25 mg/ml), PBS(pH 7.2) (~0.1 mg/ml), and ethanol.
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Alternative Distributors of [Carbocyclic Thromboxane A2]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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MSDS:
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