5-trans Prostaglandin E2 | CAS 36150-00-2

Element: prostaglandin trans

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C-S » Chemicals » trans-prostaglandin-PX69680

Identification

5-trans Prostaglandin E2

CAS:

36150-00-2

EINECS:

Molecular Formula:

C₂₀H₃₂ O₅

MDL:

SMILES:

CCCCCC(O)/C=C/[C@H]1C(O)CC(=O)C1CC=CCCCC(=O)O

Synonym:

prosta-5,13-dien-1-oicacid, 11,15-dihydroxy-9-oxo-, (5e,11a,13e,15s)- ; 5-trans prostaglandin e2 ; 9-oxo-11alpha,15s-dihydroxy-prosta-5e,13e-dien-1-oic acid ; trans-dinoprostone ; 5-trans-pge2 ; 5,6-trans-pge2 ; 5-trans-prostaglandin e2

Description

5-trans PGE2 is a naturally occuring compound and is a common impurity in commercial lots of PGE1, that shows a potency that is 18 times greater than PGE2 (5-cis PGE2) in cases of activation of adenylate cyclase in NCB-20 cell homogenates. Also has been shown to accelerate fibrinolysis by enhancing plasminogen activation mediated by tissue-type plasminogen activator, and to inhibit platelet aggregation in platelet rich plasma (PRP).