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Topotecan HCl

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Formula: C23H23N3O5.HCl
CAS: 119413-54-6
search Element: topotecan

Identification

Structural Formula
Topotecan HCl
CAS:
119413-54-6
EINECS:
Molecular Formula:
C23H23N3O5.HCl
MDL:
MFCD00866235
SMILES:
O[C@@]1(CC)C(C=C2C(N=C3C=CC(O)=C(CN(C)C)C3=C4)=C4CN52)=C(COC1=O)C5=O.Cl
Synonym:
hydrochloride ; skfs 104864a ; skf-104864a ; levulan-13c ; topotecan hcl ; 5-ala hcl-13c ; skf-s 104864-a ; nogitecan hcl ; nsc 609669 ; hycamtin




Suppliers

Aozeal Certified Standards (AOCS), Inc.
T0113.01
Evonik ( formerly Wilshire Technologies, Inc. )
E12484992
CSNpharm, Inc.
CSN12236
Wanko Chemical Co., Ltd.
WC6241872
Hefei Hirisun Pharmatech Co., Ltd
HR010146
Leap Chem Co., Ltd
LC4681404
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CAS equal suppliers

Topotecan Hydrochloride
Santa Cruz Biotechnology, Inc.
204919
topotecan hydrochloride
Indofine Chemical Co, Inc.
06-1277
Topotecan hydrochloride
Molekula
85474031
Topotecan Hydrochloride
Pharmaffiliates Analytics & Synthetics Pvt. Limited
PA 20 42000
Topotecan hydrochloride
Dayang Chem (Hangzhou) Co.,Ltd.
DC14265704
Topotecan hydrochloride
Hangzhou Verychem Science & Technology Co., Ltd.
HVST220811040
Topotecan hydrochloride
BOC Sciences
BS5521656
Topotecan hydrochloride
Autech Industry Co.,Limited
AIC12424968
Topotecan hydrochloride
AK Scientific, Inc.
AS8742622
Topotecan Hydrochloride
Exim Corporation
EC7362208
Topotecan hydrochloride
Ambeed, Inc.
A122669
Topotecan hydrochloride
Ascender Chemical Co.,Ltd
ACC11504600
Topotecan hydrochloride
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI317412696
Topotecan hydrochloride
Xingrui Industry Co., Limited
XIL13345336
Topotecan hydrochloride
Gihi Chemicals Co., Limited
GCL12424968
Topotecan hydrochloride
Shandong SanYoung Industry Co., Ltd
SSI16106440
Topotecan hydrochloride
Chemlyte Solutions
CS8282484
Topotecan Hydrochloride Labeled d6
Santa Cruz Biotechnology, Inc.
sc-356167
(S)-10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride
Chemieliva Pharmaceutical Co., Ltd.
CP83160249480
(S)-10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride
3B (Wuhan) Scientific Corporation
378408235224
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-monohydrochloride, (4S)-
BLD Pharmatech Ltd
BP40320120960

Prices & Availability




Data is processed


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Properties for Topotecan HCl

Molecular Weight:
457.91 g·mol−1
Melting point:
213-218 °C
Boiling point:
782.9° C at 760 mmHg (Predicted)
Solubility:
Soluble in methanol, water (92 mg/ml at 25° C), DMSO (92 mg/ml at 25° C), ethanol (<1 mg/ml at 25° C), and 1: 1 solution of DMSO: PBS (pH 7.2, ~0.5 mg/ml).
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Hazard Statements

GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:
R25 - Toxic if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R46 - May cause inheritable genetic damage
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
T
Hazard symbol T
Storage temperature :
Refrigerator
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Alternative Distributors of [Topotecan HCl]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Unispec Chemicals Co. | Molekula GmbH | Suzhou Highfine Biotech Co.,Ltd. | 3B Scientific Corporation | Shanghai Eagle Chemical Co., Ltd. | Afine Chemicals Limited | Xiang Ding Chemical International Co., Ltd | Nantong Chem-Tech. (Group) Co., Ltd. | Jiangsu Honghui Pharmaceutical Co., Ltd. | Pharmasi Chemicals Co., Ltd. | Melone Pharmaceutical Co., Ltd. | New Dragon Industrial Co., Ltd | Zhejiang Esun Chemical Co., Ltd. | Shanghai Tauto Biotech Co., Ltd. | Hubei Honch Pharmaceutical Co., Ltd. | Hangzhou Hysen Pharma Co., Ltd. | Genatal Life Science Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai Yingxuan Chempharm Co., Ltd. | Shanghai AOKChem Group Limited | Share Chemical Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Ark Pharm, Inc. | Sanowart Group Co., Ltd. | Bepharm Ltd. | Lanospharma Laboratories Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Jinan Great Chemical Co., Ltd. | Bichem Lab Co., Ltd. | East Chemical Industry Co., Ltd. | API Vanguard | Cfm Oskar Tropitzsch GmbH | Yongyi Chemicals Group Co., Ltd. | Pharmfar Co., Ltd. | Watson International Ltd | Greenlife Biotechnology Co.,Ltd. | BOC Sciences | Taizhou Creating Chemical Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Wanko Chemical Co., Ltd. | Haihang Industry Co., Ltd. | Clearsynth Canada INC.

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