Tamoxifen | CAS 10540-29-1 | Chemical-Suppliers

Element: tamoxifen

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C-S » Chemicals » tamoxifen-PX860739

Identification

Tamoxifen

CAS:

10540-29-1

EINECS:

234-118-0

Molecular Formula:

C₂₆H₂₉NO

MDL:

SMILES:

CC/C(=C(C1=CC=CC=C1)/C2=CC=C(C=C2)OCCN(C)C)/C3=CC=CC=C3

Synonym:

c07108 ; tamoxen ; tamoxifen ; genox ; ici47699 ; nolvadex-d ; mammaton ; z-tamoxifen ; novaldex ; tamoxiefen

Description

Tamoxifen is a selective estrogen response modifier (SERM), PKC (protein kinase C) inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells. Tamoxifen induces apoptosis in human malignant glioma cell lines. Tamoxifen is an activator of ER α and ER β.

Suppliers

H&Z Industry Co.,Ltd

HIC180720

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI6212484

Wuhan PharmChem Co., LTD.

WP225675

Chemlyte Solutions

CS162486

Aecochem Corp.

AC126378

Hangzhou Lingrui Chemical Co., Ltd.

HLC3151260

Sigma-Aldrich International GmbH

SI288864

Carbone Scientific Co., Ltd.

CS252756

CM Fine Chemicals

CFC153612

AK Scientific, Inc.

AS171513

Leap Chem Co., Ltd

LC162486

Santa Cruz Biotechnology, Inc.

208414

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CAS equal suppliers

Tamoxifen, 98%

Alfa (A Johnson Matthey Company)

A4481344

Ethanamine, 2-[4-[(1z)-1,2-diphenyl-1-butenyl]phenoxy]-n,n-dimethyl-

Angene International Limited

AGN-PC-0NW2YC

Prices & Availability

Data is processed

Properties for Tamoxifen

Molecular Weight:

371.51 g·mol−1

Density:

~1.0 g/cm³ (Predicted)

Melting point:

97-98 °C(lit.)

Boiling point:

~482.3 °C at 760 mmHg (Predicted)

Solubility:

Soluble in Dichloromethane

Safety & Transport Information

Risk Codes:

R36/37/38 - Irritating to eyes, respiratory system and skin
R45 - May cause cancer
R60 - May impair fertility
R61 - May cause harm to the unborn child
R64 - May cause harm to breast-fed babies

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use

Hazard Symbols:

T, Xi

Storage temperature :

2-8°C

Alternative Distributors of [Tamoxifen]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified