Rapamycin | CAS 53123-88-9 | Chemical-Suppliers

Element: rapamycin

Page Content Identification Properties Suppliers Prices & Availability Get Quick Quote ☰

Identification Properties Suppliers Prices & Availability Get Quick Quote

C-S » Chemicals » rapamycin-PX1135036

Identification

Rapamycin

CAS:

53123-88-9

EINECS:

Molecular Formula:

C₅₁H₇₉NO₁₃

MDL:

MFCD00867594

SMILES:

CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)O)C)C)O)OC)C)C)C)OC

Synonym:

Description

Rapamycin is a member of the macrolide immunosuppressant family and a FRAP inhibitor. Rapamycin exhibits binding and inhibitory actions to the FK506 binding protein (FKBP5) proline rotamase via simultaneous binding by FKBP12 and FRAP. FRAP (RAFT1) proteins exhibit homology to PI 4- and PI 3-kinases, which have PI 4-kinase and autophosphorylating activities.The rapamycin/FKBP complex does not inhibit the FRAP PI 4-kinase activity, but does inhibit FRAP autophosphorylation. Rapamycin is unique in its ability to inhibit lymphokine induced cell proliferation at the G₁ and S phase as well as an irreversible cellular arrest at the G₁ phase in S. cerevisiae cells. It also exhibits selective signal blocking leading to the activation of p70/85 S6 kinase, which is potentially due to the inhibition of FRAP autophosphorylation or protein kinase activity. Angiogenesis inhibition is also exhibited, possibly through the inhibition of the Akt pathway. Rapamycin is an inhibitor of mTOR.

Suppliers

OPQ Chemical Co., Ltd

OC189567

Aozeal Certified Standards (AOCS), Inc.

S0013.00

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI6212484

Create Chemical Co., Ltd.

CC225675

Chemlyte Solutions

CS162486

Shandong Minglang Chemical Co., Ltd

SMC3151260

Lori Industry Co., Ltd

LI198594

Refine Chemical Co.,Ltd.

RCC216864

Shandong Lanhai Industry Co.,Ltd.

SLIC2971485

Autech Industry Co.,Limited

AIC243972

Unilong Industry Co.,Ltd

UIC216864

Ambeed, Inc.

A656002

Aea.ltd

A63126

JieJie Group Co., Ltd.

JG198594

A.G. Scientific

AS135405

Guangzhou Topwork Chemical Co., Ltd.

GTC3241296

Hangzhou Cherry Pharmaceutical Technology Co., Ltd.

HCPT4592295

X´ian Taicheng Chem Co., Ltd

XTC2611044

Hangzhou Verychem Science & Technology Co., Ltd.

HVST4322160

Xiamen Equation Chemical Co.,Ltd

XECC2881440

Sancai Industry Co.,Ltd.

SIC216864

Aecochem Corp.

AC126378

CSNpharm, Inc.

CSN16385

Hangzhou Keying Chem Co., Ltd.

HKC2701080

Sigma-Aldrich International GmbH

SI288864

scienTEST - bioKEMIX GmbH

S-B225900

Finetech Industry Limited

FIL225900

Carbone Scientific Co., Ltd.

CS252756

Pharmacore Co., Limited

PL207621

Hefei Hirisun Pharmatech Co., Ltd

HR011428

Iris Biotech GmbH

LS-1056

CM Fine Chemicals

CFC153612

AK Scientific, Inc.

AS171513

Xingrui Industry Co., Limited

XIL2611044

Capot Chemical Co., Ltd.

16645

Zehao Industry Co., Ltd.

ZI216648

Amadis Chemical Company Limited

ACCL2791395

Leap Chem Co., Ltd

LC162486

Santa Cruz Biotechnology, Inc.

3504

Get Quick Quote

CAS equal suppliers

Rapamicin

Aea.ltd

A63126

Sirolimus

Crystal Pharma (Gadea Grupo Farmacéutico)

CP3781512

Sirolimus

Medibro Corporation Limited

MCL243972

Sirolimus

LGM Pharma

LP90270

Sirolimus

Purestar Chem Enterprise Co., Ltd.

PCE3061224

Sirolimus

Pharmacore Co., Limited

PL207621

Sirolimus

Wanko Chemical Co., Ltd.

WC216648

Sirolimus

Manchester Organics Limited

H51160

Sirolimus

Jiwan Pharmaceutical Technology Co., Ltd.

JPT3691476

Sirolimus

Aea.ltd

A63126

Sirolimus

Shandong SanYoung Industry Co., Ltd

SSI3151260

Sirolimus

Nantong Xindao Biotech Ltd

NXB234936

Rapamycin, 99+%

Alfa (A Johnson Matthey Company)

A4801440

Rapamycin(Sirolimus)

Skyrun Industrial Co., Ltd.

SI10803240

Rapamycin (Sirolimus)

Excenen Pharmatech Co., Ltd.

EX-A1044

Rapamycin (Sirolimus)

Shandong Ench Chemical Co.,Ltd

SECC12606300

Rapamycin (Sirolimus)

BOC Sciences

BS5041512

rapamycin from streptomyces hygroscopicus

Indofine Chemical Co, Inc.

Bio-954

rapamycin from streptomyces*hygroscopicus

Gihi Chemicals Co., Limited

GCL442817712

rapamycin from streptomyces*hygroscopicus

XD BIOCHEMS Ltd

XB24607380

rapamycin from streptomyces*hygroscopicus

Nantong Xindao Biotech Ltd

NXB426417056

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methyleth

BLD Pharmatech Ltd

BP108000324000

Prices & Availability

Data is processed

Properties for Rapamycin

Molecular Weight:

914.17 g·mol−1

Density:

1.18 g/cm³ (Predicted)

Melting point:

183-185° C

Boiling point:

973.02° C at 760 mmHg (Predicted)

Solubility:

Soluble in DMSO (25 mg/ml), ethanol (up to 50 mg/ml), chloroform (5 mg/ml), methanol (25 mg/ml), ether, and acetone. Insoluble in water.

Safety & Transport Information

coming up soon

Alternative Distributors of [Rapamycin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified