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seco Rapamycin Sodium Salt

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Formula: C51H79 N O13 . Na
CAS: 148554-65-8
search Element: rapamycin sodium salt seco
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Identification

Structural Formula
seco Rapamycin Sodium Salt
CAS:
148554-65-8
EINECS:
Molecular Formula:
C51H79 N O13 . Na
MDL:
SMILES:
C[C@@H]1CC[C@H](O[C@]1(C(=O)C(=O)N2CCCC[C@H]2C(=O)[O-])O)C[C@@H](/C(=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@@H]([C@@H](/C(=C/[C@@H](C)C(=O)/C=C[C@H](C)C[C@@H]3CC[C@H]([C@@H](C3)OC)O)/C)O)OC)/C)OC.[Na+]
Synonym:
2-piperidinecarboxylicacid,1-[oxo[tetrahydro-2-hydroxy-6-[14-hydroxy-22-(4-hydroxy-3-methoxycyclohexyl)-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15,19-docosapentaenyl]-3-methyl-2h-pyran-2-yl]acetyl]-,monosodium salt, [2r-[2a,2(s*),3a,6b[2s*,3e,5e,7e,9s*,11r*,13r*,14r*,15e,17r*,19e,21r*,22(1s*,3r*,4r*)]]]-(9ci) ; seco rapamycin sodium salt, >85% by hplc ; seco rapamycin sodium salt


Description

seco Rapamycin Sodium Salt is a decomposition product of Rapamycin which can function as an antifungal agent. seco Rapamycin Sodium Salt is the open ring conformation of Rapamycin. Studies suggest that seco Rapamycin Sodium Salt is impermeable to the apical membrane in Caco-2 cells. It has also been observed that seco Rapamycin Sodium Salt can be secreted across the apical membrane, which can be inhibited by the P-gp inhibitor, LY335979. In contrast, Rapamycin is cell permeable and can functions as a CYP3A4/P-gp substrate.


Suppliers

Aozeal Certified Standards (AOCS), Inc.
S0013.01
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Santa Cruz Biotechnology, Inc.
212918
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Prices & Availability




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Properties for seco Rapamycin Sodium Salt

Molecular Weight:
936.161 g·mol−1
Melting point:
120-122 °C
Solubility:
Solubility: Soluble in Methanol and Water
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Safety & Transport Information

Storage temperature :
Amber Vial, -20 °C Freezer, Under Inert Atmosphere
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Alternative Distributors of [seco Rapamycin Sodium Salt]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

Mol File:
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MSDS:
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