15(R)-Prostaglandin E1 | CAS 20897-91-0

Element: prostaglandin

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C-S » Chemicals » prostaglandin-PX73560

Identification

15(R)-Prostaglandin E1

CAS:

20897-91-0

EINECS:

Molecular Formula:

C₂₀H₃₄ O₅

MDL:

SMILES:

CCCCC[C@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)O)O)O

Synonym:

Cyclopentaneheptanoicacid, 3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-, stereoisomer (8CI) ; 15-Epi-PGE1 ; 15-Epiprostaglandin E1 ; Prost-13-en-1-oic acid,11,15-dihydroxy-9-oxo-, (11a,13E,15R)- (9CI)

Description

15(R)-PGE₁ is the “unnatural” C-15 stereoisomer of PGE₁. It is basically inactive biologically when compared to PGE₁. It is a non-competitive inhibitor of 15-hydroxy PGDH with an IC50 of 189 µM.