Prostaglandin E3 | CAS 802-31-3 | Chemical-Suppliers

Element: prostaglandin

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C-S » Chemicals » prostaglandin-PX80826

Identification

Prostaglandin E3

CAS:

802-31-3

EINECS:

Molecular Formula:

C₂₀H₃₀O₅

MDL:

MFCD00065758

SMILES:

CC/C=CC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1C/C=CCCCC(=O)O)O)O

Synonym:

prostaglandin e3 ; (5z,13e,15s,17z)-11α,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic acid ; pge3 ; (5z,11a,13e,15s,17z) 11,15-dihydroxy-9-oxo-prosta-5,13,17-trien-1-oic acid ; 9-oxo-11alpha,15s-dihydroxy-prosta-5z,13e,17z-trien-1-oic acid

Description

Prostaglandin E₃ is formed via the COX metabolism of eicosapentaenoic acid, where in human ocular tissue, it comprises 2.4% of the COX products formed. When applied to the eyes of a rabbit, a 1 μg dose of PGE₃ decreases intraocular pressure from 21 mmHg to about 17 mmHg.