PDGFR Tyrosine Kinase Inhibitor II | CAS 249762-74-1

Element: inhibitor tyrosine kinase pdgfr

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C-S » Chemicals » pdgfr-tyrosine-kinase-inhibitor-PX79371

Identification

PDGFR Tyrosine Kinase Inhibitor II

CAS:

249762-74-1

EINECS:

Molecular Formula:

C₂₁H₁₈N₂O₃

MDL:

Synonym:

(5-butanoate-1h-2-indolyl)(1h-2-indolyl)-methanone ; pdgfr tyrosine kinase inhibitor ii ; [2-(1h-2-indolycarbonyl)-1h-5-indolyl]butanoate ; [2-(1h-2-indolylcarbonyl)-1h-5-indolyl]butanoate ; butanoic acid, 2-(1h-indol-2-ylcarbonyl)-1h-indol-5-yl ester ; pdgf receptor tyrosine kinase inhibitor ii ; d-65476

Description

PDGFR Tyrosine Kinase Inhibitor II is a cell-permeable isothiourea compound that specifically, rapidly and reversibly perturbs MreB function without affecting eukaryotic actin polymerization. PDGFR Tyrosine Kinase Inhibitor II is reported to affect the growth and morphology of Caulobacter crescentus, convert rod-shaped E. coli to round cells, and block DNA segregation without affecting DNA replication. PDGFR Tyrosine Kinase Inhibitor II is suspected to interact with MreB's nucleotide binding pocket and is useful for the temporal analysis of MreB function.