PDGFR Tyrosine Kinase Inhibitor IV | CAS 627518-40-5

Element: inhibitor tyrosine kinase pdgfr

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Identification

PDGFR Tyrosine Kinase Inhibitor IV

CAS:

627518-40-5

EINECS:

Molecular Formula:

C₁₈H₁₆ F N₃ O₂

MDL:

SMILES:

COC1=C(C=C2C(=C1)CC3=C2NN=C3NC4=CC(=CC=C4)F)OC

Synonym:

(6,7-Dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)(3-fluorophenyl)amine ; Indeno[1,2-c]pyrazol-3-amine,N-(3-fluorophenyl)-1,4-dihydro-6,7-dimethoxy-

Description

PDGFR Tyrosine Kinase Inhibitor IV is a indenopyrazole compound that displays potent antiproliferative properties in human tumor cell lines. It acts as a reversible ATP-competitive inhibitor of PDGFR but exhibits less actibity towards Lck, c-Src, and Fyn while exhibiting little to no inhibition toward VEGFR, HER-2, Cdk's-1,-2,-4 &-7, bFGFR-1 and EGFR. PDGFR Tyrosine Kinase Inhibitor IV is cell-permeable. PDGFR Tyrosine Kinase Inhibitor IV is an inhibitor of c-Abl, PDGFR-α and PDGFR-β.

Suppliers

Amadis Chemical Company Limited

ACCL527026350

Santa Cruz Biotechnology, Inc.

205794

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CAS equal suppliers

JNJ-10198409

ShangHai Biochempartner Co., Ltd.

BCP08276

N-(3-Fluorophenyl)-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine

Hangzhou Keying Chem Co., Ltd.

HKC1728069120

Prices & Availability

Data is processed

Properties for PDGFR Tyrosine Kinase Inhibitor IV

Molecular Weight:

325.3 g·mol−1

Density:

~1.37 g/cm³ (Predicted)

Melting point:

154° C

Boiling point:

~528.77° C at 760 mmHg (Predicted)

Solubility:

Soluble in DMSO (>10 mg/ml), water (<2 mg/ml), and methanol.

Safety & Transport Information

coming up soon

Alternative Distributors of [PDGFR Tyrosine Kinase Inhibitor IV]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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MSDS:

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