Identification
PARP Inhibitor XI, DR2313
Molecular Formula:
C8 H1 0 N2 OS
SMILES:
CC1=NC(=O)C2=C(N1)CCSC2
Synonym:
2-methyl-1-sulfanyl-1h,4h,5h,7h,8h-pyrano[4,3-d]pyrimidin-4-one ; parp inhibitor xi, dr2313 ; 4h-thiopyrano[4,3-d]pyrimidin-4-one,3,5,7,8-tetrahydro-2 ; 3,5,7,8-tetrahydro-2-methyl-4h-thiopyrano[4,3-d]pyrimidin-4-one ; 1,5,7,8-tetrahydro-2-methyl-4h-thiopyrano[4,3-d]pyrimidin-4-one ; sc-202756 ; dr 2313 ; 7,8-dihydro-2-methyl-1h-thiopyrano[4,3-d]pyrimidin-4(5h)-one
Description
PARP Inhibitor XI, DR2313 is a water soluble pyrimidinone compound that functions as a PARP (Poly(ADP-ribose) polymerase) inhibitor. PARP (Poly(ADP-ribose) polymerase) function by triggering DNA repair mechanisms and activating apoptosis in damaged cells. Studies show that DR2313 competes with NAD+ but does not display selectivity among PARP-1 and PARP-2. In addition, in vitro studies of cerebral ischemia exhibiting an overactivation of PARP show that ischemic damage can be reduced by introducing DR2313.
Suppliers
Santa Cruz Biotechnology, Inc.
202756
Dayang Chem (Hangzhou) Co.,Ltd.
DC310012400
CAS equal suppliers
DR 2313
Leap Chem Co., Ltd
LC126378
DR 2313
Hangzhou J&H Chemical Co., Ltd.
HJC217868
DR 2313
Finipharma Ltd
F98196
DR 2313
U-Chemo Scientific (Shanghai) Co.,Ltd.
US2661064
7,8-Dihydro-2-methyl-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one
Simagchem Corporation
SC882026460
7,8-Dihydro-2-methyl-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one
Amadis Chemical Company Limited
ACCL1302065100
7,8-Dihydro-2-methyl-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one
Xiamen Hisunny Chemical Co., Ltd.
XHC1386055440
7,8-Dihydro-2-methyl-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one
Xiamen Equation Chemical Co.,Ltd
XECC1344067200
Prices & Availability
Data is processed
Properties
Safety & Transport
Alternative Distributors
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Properties for PARP Inhibitor XI, DR2313
Molecular Weight:
182.2428 g·mol−1
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Safety & Transport Information
Storage temperature :
Store at +4 °C
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Alternative Distributors of [PARP Inhibitor XI, DR2313]
Producers or manufacturers change the product range from time to time.
Currently there are no other manufacturers known.