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Olomoucine II

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Formula: C19H26N6O2
CAS: 500735-47-7
search Element: olomoucine

Identification

Structural Formula
Olomoucine II
CAS:
500735-47-7
EINECS:
Molecular Formula:
C19H26N6O2
MDL:
MFCD06411574
SMILES:
CCC(CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3O)N=CN2C(C)C
Synonym:
2-[[[2-[[(1r)-1-(hydroxymethyl)propyl]amino]-9-(1-methylethyl)-9h-purin-6-yl]amino]methyl]phenol ; nsc736738 ; olomoucine ii, 6-[(2-hydroxybenzyl)amino]-2-[1-(hydroxymethyl)propylamino]- 9-isopropylpurine


Description

Olomoucine II is a selective inhibitor of Cdk1(CDK1)/cyclin B (IC50 = 20 nM). Olomoucine II is a potent cytotoxin in tumor cells: IC50 = 5.3 μM against MCF7 cells, IC50 = 11.1 μM against K562 cells, IC50 = 3.0 μM against CEM cells, IC50 = 6.3 μM against HOS cells, and IC50 = 6.3 μM against G361 cells.


Suppliers

Leap Chem Co., Ltd
LC4681404
Santa Cruz Biotechnology, Inc.
202750
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Properties for Olomoucine II

Molecular Weight:
370.454 g·mol−1
Density:
1.32
Melting point:
254.54° C (Predicted)
Boiling point:
618.47° C at 760 mmHg (Predicted)
Solubility:
chloroform: 50 mg/mL, soluble
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Safety & Transport Information

Safety Codes:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
Storage temperature :
-20°C
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Alternative Distributors of [Olomoucine II]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences

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MSDS:
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