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Oligomycin C

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Formula: C45H74O10
CAS: 11052-72-5
search Element: oligomycin

Identification

Structural Formula
Oligomycin C
CAS:
11052-72-5
EINECS:
234-276-0
Molecular Formula:
C45H74O10
MDL:
MFCD00043231
SMILES:
CC[C@H]1CC[C@@H]2[C@@H]([C@@H]([C@H]([C@@]3(O2)CC[C@H]([C@H](O3)CC(C)O)C)C)OC(=O)/C=C/[C@H]([C@@H]([C@H](C(=O)[C@H]([C@@H]([C@H](C(=O)[C@@H]([C@@H]([C@H](C/C=C/C=C1)C)O)C)C)O)C)C)O)C)C
Synonym:
12-deoxyoligomycin a ; oligomycin c, streptomyces diastatochromogenes ; oligmycin c ; oligomycin a, 12-deoxy- ; oligomycin c


Description

Oligomycin C is part of a class of macrolide antibiotics and is a potent inhibitor of cell regulatory volume decrease (RVD). Oligomycin has been shown to inhibit ATP synthase by blocking the ATP5 (mitochondrial F1F0-ATPase). Doxorubicin-resistant HepG2 cell studies report that oligomycin can inhibit the activity of P-glycoprotein and induce apoptosis.


Suppliers

Aea.ltd
A168336
Santa Cruz Biotechnology, Inc.
202263
Dayang Chem (Hangzhou) Co.,Ltd.
DC7442976
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Properties for Oligomycin C

Molecular Weight:
775.06 g·mol−1
Density:
1.12 g/cm3 (Predicted)
Melting point:
195-200° C
Boiling point:
876.18° C at 760 mmHg (Predicted)
Solubility:
Soluble in 100% ethanol, methanol, DMF, and DMSO. Insoluble in water.
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Safety & Transport Information

Risk Codes:
R22 - Harmful if swallowed
Hazard Classes:
6.1(b)
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
-20°C
RID/ADR certification :
2811
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Alternative Distributors of [Oligomycin C]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Cfm Oskar Tropitzsch GmbH

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MSDS:
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