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Isoniazid-d4

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Formula: C6H3D4N3O
CAS: 774596-24-6
search Element: isoniazid

Identification

Structural Formula
Isoniazid-d4
CAS:
774596-24-6
EINECS:
Molecular Formula:
C6H3D4N3O
MDL:
SMILES:
[2H]C1=C(N=C(C(=C1C(=O)NN)[2H])[2H])[2H]
Synonym:
fsr-3-d ; tubazid-d4 ; 5015 r.p.-d4 ; rp-5015-d4 ; isonicotinic acid-d4 hydrazide ; fsr-3-d3 ; isonicotinylhydrazine-d4 ; armazid-d4 ; isoniazid-d4 ; arma


Description

Isoniazid-d4 is a labeled form of isoniazid that is used as an antibiotic and inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. This compound is both an inhibitor and inducer of various isoforms of cytochrome P450, a family of enzymes extensively involved in the metabolism of xenobiotics. CYP isoforms induced by this product include CYP2E1. Isoniazid reversibly inhibits CYP2C19 and CYP3A4 and inactivates CYP1A2 and CYP2A6. The deuterated form is useful in kinetic isotope effect studies and as an internal standard for NMR experiments.


Suppliers

Santa Cruz Biotechnology, Inc.
218611
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Properties for Isoniazid-d4

Molecular Weight:
141.16 g·mol−1
Melting point:
171.40C
Solubility:
Soluble in Water
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Safety & Transport Information

Storage temperature :
Refrigerator
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Alternative Distributors of [Isoniazid-d4]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | Clearsynth Canada INC.

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MSDS:
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