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Isoniazid

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Formula: C6H7N3O
CAS: 54-85-3
search Element: isoniazid
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Identification

Structural Formula
Isoniazid
CAS:
54-85-3
EINECS:
200-214-6
Molecular Formula:
C6H7N3O
MDL:
MFCD00006426
SMILES:
C1=CN=CC=C1C(=O)NN
Synonym:
hyzyd ; hia ; fsr-3 ; cedin ; in-73 ; fsr3 ; inah ; gink ; fsr 3 ; inh


Description

Isoniazid is a front-line antituberculosis agent. Generates nitric oxide when activated by KatG. Isoniazid is also a strong inhibitor of DPH metabolism. This compound is both an inhibitor and inducer of various isoforms of cytochrome P450, a family of enzymes extensively involved in the metabolism of xenobiotics. CYP isoforms induced by this product include CYP2E1. Isoniazid reversibly inhibits CYP2C19 and CYP3A4 and inactivates CYP1A2 and CYP2A6.


Suppliers

Chemlyte Solutions
CS162486
+
FUDI Chemical Co. Ltd.
FCC198792
+
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI6212484
+
Kowa American Corp.
KAC171684
Sinogreat Enterprise Ltd.
SE225675
+
IBIS Chemie International
ICI225900
+
Xiamen Equation Chemical Co.,Ltd
XECC2881440
+
Hainan Zhongxin Chemical Co., Ltd.
HZC3061224
+
Sigma-Aldrich International GmbH
SI288864
+
Xiamen Kinbester Co., Ltd.
XK234702
+
Capot Chemical Co., Ltd.
45468
+
Leap Chem Co., Ltd
LC162486
+
Santa Cruz Biotechnology, Inc.
205722
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Prices & Availability




Data is processed


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Properties for Isoniazid

Molecular Weight:
137.14 g·mol−1
Density:
~1.2 g/cm3 (Predicted)
Melting point:
171-173 °C(lit.)
Boiling point:
329.79° C (Predicted)
Flash point:
>250 °C
Solubility:
Soluble in water (50 mg/ml), ethanol (27 mg/ml at 25° C), DMSO (27 mg/ml at 25° C), and methanol.
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Safety & Transport Information

Risk Codes:
R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R38 - Irritating to skin
R40 - Limited evidence of a carcinogenic effect
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S37 - Wear suitable gloves
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
Refrigerator
RID/ADR certification :
2811
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Alternative Distributors of [Isoniazid]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | DKSH International AG | Finetech Industry Limited | BOC Sciences | Inter-Chemical Ltd. | Wuxi Mizat Chemical Technology Co., Ltd. | Jinan Great Chemical Co., Ltd. | Nanjing Chemcial Material Corp | Lanospharma Laboratories Co., Ltd. | Yangzhou Princechem Co., Ltd. | New Dragon Industrial Co., Ltd | VAV Life Sciences Pvt. Ltd. | Yangzhou Pharmaceutical Co., Ltd. | Watson International Ltd | Santec Chemicals Corp. | Zhejiang Jiangbei Pharmaceutical Co., Ltd. | Hallochem Pharma Co., Ltd. | G. Amphray Laboratories | Hangzhou Think Chemical Co., Ltd. | Changsha Huajia Chemical Science Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Ningbo Pangs Chem Int'l Co., Ltd. | Clearsynth Canada INC. | Win-Win Chemical Co., Limited | Discovery Fine Chemicals Limited | Zibo Panxin Pharmaceutical Co., Ltd. | Unispec Chemicals Co. | TRUST&WE Co., Ltd. | Haihang Industry Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Skyrun Industrial Co., Ltd. | East Chemical Industry Co., Ltd. | Aopharm | Zhejiang Kaili Industrial Co., Ltd.

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