13(S)-HODE | CAS 29623-28-7 | Chemical-Suppliers

Element: hode

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C-S » Chemicals » hode-PX78093

Identification

13(S)-HODE

CAS:

29623-28-7

EINECS:

Molecular Formula:

C₁₈H₃₂ O₃

MDL:

MFCD00065833

SMILES:

CCCCC[C@H](O)/C=C/C=CCCCCCCCC(O)=O

Synonym:

13(s)-hydroxy-9(z),11(e)-octadecadienoic acid ; 13(s)-hod ; (s)-coriolic acid ; 9,11-octadecadienoicacid, 13-hydroxy-, (e,z)-(s)- (8ci) ; 13(s)-hode ; (13s,9z,11e)-13-hydroxy-9,11-octadecadienoic acid ; (9z,11e,13s)-13-hydroxy-9,11-octadecadienoic acid ; 13(s)-hydroxyoctadeca-9z,11e-dienoic acid ; 9,11-octadecadienoicacid, 13-hydroxy-, (9z,11e,13s)- ; 9,11-octadecadienoic acid, 13-hydroxy-,[s-(e,z)]- ; (13s,9z,11e)-13-hydroxy-9,11-octadecadienoicacid ; (9z,11e,13s)-13-hydroxyoctadecadienoic acid ; 13s-hydroxy-9z,11e-octadecadienoic acid ; 13s-hode ; (+)-coriolic acid ; 13-hydroxy-9c,11t-octadecadienoic acid ; 13(s)-hydroxyoctadeca-9z,11e-dienoic acid (13-hode) ; l-13-hydroxy-cis-9,trans-11-octadecadienoic acid

Description

13(S)-HODE is produced by incubation of linoleic acid with plant and mammalian lipoxygenases. Shown to inhibit the adhesion of tumor cells to the endothelium at concentrations around 1 µM,1,2 and down regulates the expression of the IRGpIIb/IIIa receptor. 13(S)-HODE is an activator of PPAR γ.