13(R)-HODE | CAS 10219-69-9 | Chemical-Suppliers

Element: hode

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C-S » Chemicals » hode-PX70733

Identification

13(R)-HODE

CAS:

10219-69-9

EINECS:

Molecular Formula:

C₁₈H₃₂ O₃

MDL:

SMILES:

CCCCCC(C=CC=CCCCCCCCC(=O)O)O

Synonym:

9,11-octadecadienoic acid, 13-hydroxy-, (r-(e,z))- ; (r)-coriolicacid ; (r-(e,z))-13-hydroxy-9,11-octadecadienoic acid ; (r)-13-hydroxy-cis-9,trans-11-octadecadienoic acid ; 13r-hydroxy-9-cis,11-trans-octadecadienoic acid ; 13r-hode ; 9,11-octadecadienoicacid, 13-hydroxy-, (e,z)-(r)- (8ci) ; 9,11-octadecadienoic acid, 13-hydroxy-,[r-(e,z)]- ; 13r-hydroxy-9z,11e-octadecadienoic acid ; 13(r)-hode ; coriolic acid ; (r,9z,11e)-13-hydroxy-9,11-octadecadienoic acid ; 9,11-octadecadienoicacid, 13-hydroxy-, (9z,11e,13r)- ; 13(r)-hydroxy-9,11-octadienoic acid

Description

13(R)-HODE is an enantiomer of 13-HODE produced when linoleic acid is incubated with soybean lipoxygenase. The existence of 13(R)-HODE in the supernatants and membranes of cultured bovine endothelial cells has been attributed to COX metabolism. 13(R)-HODE is a weak (IC₅₀ = 2.7 µM) inhibitor of U-46619-induced platelet aggregation.