Gramicidin A | CAS 11029-61-1 | Chemical-Suppliers

Element: gramicidin

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C-S » Chemicals » gramicidin-PX68197

Identification

Gramicidin A

CAS:

11029-61-1

EINECS:

Molecular Formula:

C₉₉H₁₄₀N₂₀O₁₇

MDL:

MFCD00466944

SMILES:

C[C@@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C(C)C)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC5=CNC6=CC=CC=C65)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC7=CNC8=CC=CC=C87)C(=O)NCCO)NC(=O)CNC(=O)[C@H](C(C)C)NC=O

Synonym:

hco-val-gly-ala-d-leu-ala-d-val-val-d-val-trp-d-leu-trp-d-leu-trp-d-leu-trp-nhch2ch2oh ; gramicidin a from bacillus brevis ; grimicidin a ; ga ; ohc-nh-val-gly-ala-d-leu-ala-d-val-val-d-val-trp-d-leu-trp-d-leu-trp-d-leu-trp-conch2ch2oh ; hco-val-gly-ala-d-leu-ala-d-val-val-d-val-trp-d-leu-trp-d-leu-trp-d-leu-nhch2ch2oh ; hco-x-gly-l-ala-d-leu-l-ala-d-val-l-val-d-val-l-trp-d-leu-l-trp-d-leu-l-trp-d-leu-l-trp-nhch2ch2oh ; glutaminase liver isoform, mitochondrial ; gls2 ; gramicidin a ; gramicidinafrombacillusbrevis95+% ; anti-gls2 (c-term e513) antibody produced in rabbit ; grimicidina(highpurity),bacillusbrevis ; gramicidin a, bacillus brevis ; ohc-nh-val-gly-ala-d-leu-ala-d-val-val-d-val-trp-d-leu-trp-d-leu-trp-d-leu-trp-d-leu-trp-conhch2ch2oh

Description

Gramicidin A is a naturally occurring antibiotic that acts as an ion channel-forming pentadecapeptide. Bacillus brevis produces Gramicidin and is an effective antibiotic against gram-positive organisms. Gramicidin can be used to study membrane channels because of its cation-selective, single-filing pore and has been used as a model to study ion channel proteins, and acylation of membrane proteins. The Gramicidin A channel has demonstrated to be permeable to small monovalent cations, protons, and water but impermeable to divalent cations and anions.

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203061

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DC7442976

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Prices & Availability

Data is processed

Properties for Gramicidin A

Molecular Weight:

2825.88 g·mol−1

Solubility:

Soluble in water (partly), acetic acid, DMSO (100 mg/ml), ethanol, and methanol.

Safety & Transport Information

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. An antibiotic. When heated to decomposition it emits toxic fumes of NOx.

Risk Codes:

R22 - Harmful if swallowed

Hazard Symbols: