Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) | CAS 1405-97-6

Element: aneurinolyticus gramicidin bacillus bacillus brevis from

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C-S » Chemicals » gramicidin-from-bacillus-aneurinolyticus-bacillus-brevis-PX49128

Identification

Gramicidin from Bacillus aneurinolyticus (Bacillus brevis)

CAS:

1405-97-6

EINECS:

215-790-4

Molecular Formula:

C_₉₉H_₁₄₀N_₂₀O_₁₇

MDL:

MFCD00131232

SMILES:

C[C@@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC5=CNC6=CC=CC=C65)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC7=CNC8=CC=CC=C87)C(=O)NCCO)NC(=O)CNC(=O)[C@H](C(C)C)NC=O

Synonym:

gramacidin d ; gramoderm ; gramicidins ; gramicidinn.f.xiv ; gramicidin d ; gramicidin,usp ; gramicidin complex ; gramicidin d [dubos] ; gramicidin ; aids-002001 ; aids002001 ; gramicidinum ; gramicidin (200 mg)

Description

Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) is a linear polypeptide antibiotic with a mixture of gramicidin A, B, C, and D. Gramicidin D is a channel-forming ionophore that flip-flops slowly across the membrane and is a known Pgp substrate and surprisingly was found to inhibit Pgp ATPase activity. This inhibition was reversed by other Pgp substrates suggesting a common drug binding site among MDR substrate-type drugs and chemosensitizers.

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Santa Cruz Biotechnology, Inc.

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Properties for Gramicidin from Bacillus aneurinolyticus (Bacillus brevis)

Molecular Weight:

1882.3 g·mol−1

Safety & Transport Information

Risk Codes:

R20/21 - Harmful by inhalation and in contact with skin
R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Storage temperature :

2-8°C

Alternative Distributors of [Gramicidin from Bacillus aneurinolyticus (Bacillus brevis)]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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