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GGTI 298

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Formula: C27H33 N3 O3 S
CAS: 180977-44-0
search Element: ggti

Identification

Structural Formula
GGTI 298
CAS:
180977-44-0
EINECS:
Molecular Formula:
C27H33 N3 O3 S
MDL:
MFCD06409252
SMILES:
CC(C)C[C@@H](C(=O)OC)NC(=O)C1=C(C=C(C=C1)NC[C@H](CS)N)C2=CC=CC3=CC=CC=C32.C(=O)(C(F)(F)F)O
Synonym:
ggti-298 ; ggti-298 trifluoroacetate salt ; n-4-[2(r)-amino-3-mercaptopropyl]amino-2-naphthylbenzoyl-(l)-leucine methyl ester, tfa ; n-[[4-(2-(r)-amino-3-mercaptopropyl)amino]-2-naphthylbenzoyl]leucine methyl ester trifluoroacetate salt ; n-[4-[2(r)-amino-3-mercaptopropyl]amino-2-(1-naphthalenyl)benzoyl]-l-leucinemethylestertrifluoroacetatesalt ; n-[[4-(2-(r)-amino-3-mercaptopropyl)amino]-2-naphthylbenzoyl]leucine methyl ester trifluoroacetate salt ; l-leucine,n-[4-[(2-amino-3-mercaptopropyl)amino]-2-(1-naphthalenyl)benzoyl]-, methylester, (r)- ; ggti 298 ; l-leucine,n-[4-[[(2r)-2-amino-3-mercaptopropyl]amino]-2-(1-naphthalenyl)benzoyl]-, methylester


Description

GGTI 298 has been shown to be a CAAZ peptidomimetic GGTase I (geranylgeranyltransferase I) inhibitor. This compound has been shown to cause G0-G1 cell cycle block and apoptosis in A549 cells.


Suppliers

BOC Sciences
BS96288
Amadis Chemical Company Limited
ACCL2481240
Santa Cruz Biotechnology, Inc.
361184
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CAS equal suppliers

GGTI298
ShangHai Biochempartner Co., Ltd.
BCP24854
GGTI298
Excenen Pharmatech Co., Ltd.
EX-A2390

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Properties for GGTI 298

Molecular Weight:
593.66 g·mol−1
Melting point:
99.5-100 °C
Boiling point:
734.1 °C at 760 mmHg (Predicted)
Solubility:
DMSO: 22 mg/mL
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Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
-20°C
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Alternative Distributors of [GGTI 298]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences

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Mol File:
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MSDS:
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