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Flavopiridol

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Formula: C21H20ClNO5
CAS: 146426-40-6
search Element: flavopiridol
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Identification

Structural Formula
Flavopiridol
CAS:
146426-40-6
EINECS:
Molecular Formula:
C21H20ClNO5
MDL:
MFCD00894265
SMILES:
CN1CC[C@@H]([C@@H](C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O
Synonym:
l-868275 ; vopiridol(alvocidib) ; l 868275 ; alvocidib ; flavopiridol, >=99% ; hmr 1275 ; l86-8275 ; flavopiridol ; flavopirodol ; c077990


Description

Flavopiridol is a synthetic flavone compound that inhibits the phosphorylation of cyclin-dependent kinases (Cdks) and suppresses expression of cyclin D1 and D3, interrupting the central role of Cdks in the regulation of the cell cycle and consequently promoting apoptosis. This action has been exploited in studies investigating the suppression of oncogenic proliferation, synovial hyperplasia, and joint destruction related to rheumatoid arthritis. Flavopiridol is an inhibitor of Cdk1, Cdk10, Cdk11, Cdk2, Cdk3, Cdk4, Cdk5, Cdk6, Cdk7, Cdk8 and Cdk9.


Suppliers

H&Z Industry Co.,Ltd
HIC240960
+
Aea.ltd
A84168
+
Chemlyte Solutions
CS216648
+
Carbone Scientific Co., Ltd.
CS3361008
+
CM Fine Chemicals
CFC204816
Xingrui Industry Co., Limited
XIL3481392
+
Capot Chemical Co., Ltd.
22427
+
Amadis Chemical Company Limited
ACCL3721860
+
Leap Chem Co., Ltd
LC216648
+
Santa Cruz Biotechnology, Inc.
202157
Dayang Chem (Hangzhou) Co.,Ltd.
DC3721488
+
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CAS equal suppliers

2-(2-Chlorophenyl)-5,7-dihydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-4H-chromen-4-one
Hangzhou MolCore BioPharmatech Co.,Ltd.
MC116199

Prices & Availability




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Properties for Flavopiridol

Molecular Weight:
401.84 g·mol−1
Density:
1.45 g/cm3 (Predicted)
Boiling point:
603.56° C at 760 mmHg (Predicted)
Solubility:
Soluble in chloroform, and water (slightly soluble).
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Safety & Transport Information

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Alternative Distributors of [Flavopiridol]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | Sanowart Group Co., Ltd. | Jinan Great Chemical Co., Ltd. | Gihi Chemicals Co., Limited | Lanospharma Laboratories Co., Ltd. | Taizhou Taifeng Chemical Co., Ltd. | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Watson International Ltd | Qventas, Inc. | Hangzhou Onicon Chemical Co., Ltd. | Auspure Biotechnology Co., Ltd. | Hallochem Pharma Co., Ltd. | Shanghai PI Chemicals Ltd. | Jinan Haohua Industry Co., Ltd. | Zhejiang Esun Chemical Co., Ltd. | Shanghai Yingxuan Chempharm Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Andy Chemicals CO., Ltd. | Shanghai Arbor Chemical Co., Ltd. | Shanghai Marketing Center of Yangzhou Princechem Co., Ltd. | Shanghai Sun-shine Chemical Technology Co., Ltd. | East Chemical Industry Co., Ltd. | Sino Rarechem Labs Co. Ltd.

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