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Dynamin Inhibitor II

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Formula: C17H38NBr
CAS: 1119-97-7
search Element: inhibitor dynamin
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Identification

Structural Formula
Dynamin Inhibitor II
CAS:
1119-97-7
EINECS:
214-291-9
Molecular Formula:
C17H38NBr
MDL:
MFCD00011770
SMILES:
CCCCCCCCCCCCCC[N+](C)(C)C.[Br-]
Synonym:
microcideiitm ; [m3c14n]br ; mitmab ; tetradonium ; quaternium13 ; morpant ; mtab ; cetrimide ; mytab ; ttab


Description

Dynamin Inhibitor II is a cell-permeable cationic surfactant that reversibly inhibits Dynamin I GTPase activity (IC50 = 3.15 μM) by targeting the PH domain and interfering with phospholipid binding. Dynamin Inhibitor II has been shown to block Dynamin I-dependent SVE (synaptic vesicle endocytosis) in rat brain synaptosomes and Dynamin II-dependent RME (receptor-mediated endocytosis) in non-neuronal HeLa, A431, and COS-7 cells. Inhibition is competitive with respect to PS and noncompetitive with respect to GTP. Dynamin Inhibitor II is an inhibitor of Dynamin II.


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Santa Cruz Biotechnology, Inc.
203931
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Prices & Availability




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Properties for Dynamin Inhibitor II

Molecular Weight:
336.39 g·mol−1
Melting point:
245-250 °C(lit.)
Solubility:
H2O: 10 % (w/v)
Physical Description:
white powder
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Hazard Statements

GHS05

GHS05
Corrosive
  • Corrosive to metals, category 1

Safety & Transport Information

Risk Codes:
R34 - Causes burns
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S27 - Take off immediately all contaminated clothing
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
C
Hazard symbol C
RID/ADR certification :
UN 3263 8 / PG 2
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Alternative Distributors of [Dynamin Inhibitor II]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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MSDS:
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