Dexamethasone | CAS 50-02-2 | Chemical-Suppliers

Element: dexamethasone

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C-S » Chemicals » dexamethasone-PX73228

Identification

Dexamethasone

CAS:

50-02-2

EINECS:

200-003-9

Molecular Formula:

C₂₂H₂₉FO₅

MDL:

MFCD00064136

SMILES:

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C

Synonym:

mk125 ; dxm ; dxms ; auxiron ; dezone ; mk 125 ; dexa ; hl-dex ; dexone ; corson

Description

Dexamethasone is an antiinflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC₅₀=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G₁/S transition in osteoblasts and inhibition of phosphorylation of Rb protein in vitro. Dexamethasone has been observed to induce apoptosis in human thymocytes and eosinophils, but inhibits apoptosis in neutrophils in vitro. Dexamethasone is an activator of IDO.

Suppliers

Aea.ltd

A91182

Shandong SanYoung Industry Co., Ltd

SSI4551820

Chemlyte Solutions

CS234702

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI8973588

Shandong Ench Chemical Co.,Ltd

SECC3901950

H&Z Industry Co.,Ltd

HIC2601040

Krada CPS Industry S.L

KCIS2861430

Wuhan PharmChem Co., LTD.

WP325975

R.J. Chemicals, Inc.

RC260780

Crystal Pharma (Gadea Grupo Farmacéutico)

CP5462184

Guangzhou Topwork Chemical Co., Ltd.

GTC4681872

Hangzhou Cherry Pharmaceutical Technology Co., Ltd.

HCPT6633315

Serva Electrophoresis GmbH

SE3381014

AXO Industry SA

AIS195780

X´ian Taicheng Chem Co., Ltd

XTC3771508

Hangzhou Verychem Science & Technology Co., Ltd.

HVST6243120

Caesar & Loretz GmbH

CL260780

Shanghai Worldyang Chemical Co., Ltd.

SWC4811924

Xiamen Equation Chemical Co.,Ltd

XECC4162080

Sancai Industry Co.,Ltd.

SIC3121248

Daming Changda Co., Ltd.

LLB00452

Aecochem Corp.

AC182546

Fox Chemicals GmbH

FC234702

Hangzhou Keying Chem Co., Ltd.

HKC3901560

Sigma-Aldrich International GmbH

SI4161248

scienTEST - bioKEMIX GmbH

S-B3251300

Carbone Scientific Co., Ltd.

CS3641092

AK Scientific, Inc.

AS247741

Leap Chem Co., Ltd

LC234702

Santa Cruz Biotechnology, Inc.

29059

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Dexomethasone

Capot Chemical Co., Ltd.

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AOB3421368

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Alfa (A Johnson Matthey Company)

A5761728

Dexamethasone Labeled d5 (contains d2)

Santa Cruz Biotechnology, Inc.

sc-353202

Prices & Availability

Data is processed

Properties for Dexamethasone

Molecular Weight:

392.46 g·mol−1

Density:

1.33 g/cm³ (Predicted)

Melting point:

262-264 °C(lit.)

Boiling point:

~568.2 °C at 760 mmHg (Predicted)

Solubility:

ethanol: 1 mg/mL

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
R40 - Limited evidence of a carcinogenic effect
R42/43 - May cause sensitization by inhalation and skin contact
R43 - May cause sensitisation by skin contact

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Symbols:

Xi, Xn, T, F
Hazard symbol T

Storage temperature :

2-8°C

Alternative Distributors of [Dexamethasone]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified