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Dexamethasone Acetate

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Formula: C24H31FO6
CAS: 1177-87-3
search Element: dexamethasone acetate
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Identification

Structural Formula
Dexamethasone Acetate
CAS:
1177-87-3
EINECS:
214-646-8
Molecular Formula:
C24H31FO6
MDL:
MFCD00027407
SMILES:
CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COC(=O)C)O)C)O)F)C
Synonym:
decadronal ; nsc 39471 ; decadron-la ; dectan ; dalalone l.a. ; panasone ; fortecortin ; dalalone d.p. ; dexacortisyl ; dectancyl


Description

Dexamethasone Acetate is a glucocorticoid with anti-inflammatory properties. One possible mode of action of the anti-inflammatory properties has been documented by Dexamethasone Acetate inhibitiing upregulation of ICAM-1 (intercellular adhesion molecule-1) in cultured human mast cells. The compound also displays anti mitotic activity against chemically transformed mouse fibroblasts by halting mitosis from entering the S-phase. Dexamethasone Acetate has also been determined to markedly decrease the number of activated macrophages. In addition, Dexamethasone Acetate has been observed to significantly decrease mRNA levels of TPH2 (tryptophan hydroxylase-2) in the raphe nuclei of C57/Bl6 mice.


Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI289811592
+
H&Z Industry Co.,Ltd
HIC8403360
+
Wuhan PharmChem Co., LTD.
WP10503150
+
Alfa (A Johnson Matthey Company)
A13444032
X´ian Taicheng Chem Co., Ltd
XTC12184872
+
Xiamen Equation Chemical Co.,Ltd
XECC13446720
+
Aecochem Corp.
AC5881764
+
Sigma-Aldrich International GmbH
SI13444032
+
Carbone Scientific Co., Ltd.
CS11763528
+
Leap Chem Co., Ltd
LC7562268
+
Santa Cruz Biotechnology, Inc.
204714
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Gihi Chemicals Co., Limited
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Chemlyte Solutions
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BOC Sciences
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Aozeal Certified Standards (AOCS), Inc.
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Caesar & Loretz GmbH
CL29608880

Prices & Availability




Data is processed


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Properties for Dexamethasone Acetate

Molecular Weight:
434.5 g·mol−1
Density:
1.30 g/cm3 (Predicted)
Melting point:
238-240 °C(lit.)
Boiling point:
579.39° C at 760 mmHg (Predicted)
Solubility:
Soluble in alcohol, DMSO (87 mg/ml at 25° C), water (<1 mg/ml at 25° C), ethanol (20 mg/ml at 25° C), and methanol.
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Safety & Transport Information

Risk Codes:
R43 - May cause sensitisation by skin contact
Safety Codes:
S36/37 - Wear suitable protective clothing and gloves
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
2-8°C
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Alternative Distributors of [Dexamethasone Acetate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Santec Chemicals Corp. | CCS. CHEM. Co., Ltd. | Hallochem Pharma Co., Ltd. | 3B Scientific Corporation | Changzhou An-Yuan Imp. & Exp. Corporation | Orichem International Ltd. | Long Island Pharmaceutical & Chemical Co. Ltd. | Wuhan Hezhong Biochemical Manufacture Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Benro Internatinal Co., Linc | East Chemical Industry Co., Ltd. | API Vanguard | Watson International Ltd | Xiamen Hisunny Chemical Co., Ltd. | Clearsynth Canada INC. | Haihang Industry Co., Ltd.

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