Ac-DEVD-pNA | CAS 189950-66-1 | Chemical-Suppliers

Element: devd

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C-S » Chemicals » devd-pna-PX92089

Identification

Ac-DEVD-pNA

CAS:

189950-66-1

EINECS:

Molecular Formula:

C₂₆H₃₄N₆O₁₃

MDL:

MFCD00792707

SMILES:

CC(C)C(C(=O)NC(CC(=O)O)C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C

Synonym:

acetyl-asp-glu-val-asp-(p-nitroanilide) ; ac-asp-glu-val-asp-p-nitroanilide ; caspase-3 substrate i, colorimetric ; ac-asp-glu-val-asp-paranitroanilide ; caspase-3 substrate (chromogenic) ; n-acetyl-asp-glu-val-asp-p-nitroanilide ; caspase 3/cpp32 chromogenic substrate ; ac-devd-pna ; acetyl-devd-pna ; ac-asp-glu-val-asp-pna

Description

Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) (K_m=9.7μM) and related cysteine proteases. It is also a substrate for caspase-6, caspase-7, caspase-8, and caspase-10. The sequence is based on PARP (poly(ADPribose) polymerase) cleavage site Asp216 for caspase-3. Cleavage is monitored colorimetrically at 405nm.

Suppliers

Acinopeptide Co., Ltd.

A242484

Santa Cruz Biotechnology, Inc.

311275

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Bachem AG

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Dayang Chem (Hangzhou) Co.,Ltd.

DC6822728

Prices & Availability

Data is processed

Properties for Ac-DEVD-pNA

Molecular Weight:

638.58 g·mol−1

Density:

1.4±0.1 g/cm³ (Predicted)

Boiling point:

1187.0±65.0 °C at 760 mmHg (Predicted)

Solubility:

Soluble in water (partly), DMSO, buffer, pH 7, and acetonitrile:methanol (1:1) (1 mg/ml).

Safety & Transport Information

Storage temperature :

-20°C

Alternative Distributors of [Ac-DEVD-pNA]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Shanghai Mocell Biotech Co.,Ltd.