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Cytochalasin H

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Formula: C30H39 N O5
CAS: 53760-19-3
search Element: cytochalasin

Identification

Structural Formula
Cytochalasin H
CAS:
53760-19-3
EINECS:
Molecular Formula:
C30H39 N O5
MDL:
MFCD00010539
SMILES:
CC1CC=CC2C(C(=C)C(C3C2(C(C=CC(C1)(C)O)OC(=O)C)C(=O)NC3CC4=CC=CC=C4)C)O
Synonym:
[11]cytochalasa-6(12),13,19-trien-1-one,21-(acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl-,(7s,13e,16s,18r,19e,21r)- ; paspalin p i ; aids-031241 ; cytochalasin h ; nsc305222 ; 1h-cycloundec[d]isoindol-1-one,15-(acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-,[3s-(3r*,3as*,4r*,6r*,6as*,7e,10r*,12s*,13e,15s*,15as*)]- ; aids031241 ; kodocytochalasin 1 ; 19-triene-1-one ; paspalin ; paspalin p1 ; cytochalasin h(cyth) ; paspalinpi ; cytochalasin o ; kodocytochalasin-1


Description

Cytochalasin H is used in actin polymerization studies. Cytochalasins are potent mycotoxins which bind to the barbed end of actin filaments resulting in inhibition of both the association and dissociation of subunits. Used as a tool for cytological research. These fungal toxins are related by their chemical structure characterized by a highly substituted hydrogenated isoindole ring to which is fused a macrocyclic ring. In vitro, cytochalasin H exhibits antibacterial, antifungal, nematocidal and antitumor activity.


Suppliers

Aea.ltd
A196392
Leap Chem Co., Ltd
LC5041512
Santa Cruz Biotechnology, Inc.
202119
Dayang Chem (Hangzhou) Co.,Ltd.
DC8683472
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Properties for Cytochalasin H

Molecular Weight:
493.70 g·mol−1
Density:
1.19 g/cm3
Melting point:
252-258 °C
Boiling point:
676.5°C at 760 mmHg
Flash point:
362.9°C
Solubility:
chloroform: 10 mg/mL, clear, colorless
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Safety & Transport Information

Poison by intravenous and intraperitoneal routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Risk Codes:
R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed
R63 - Possible risk of harm to the unborn child
Safety Codes:
S28 - After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
6.1(a)
Hazard Symbols:
T+
Hazard symbol T+
Storage temperature :
2-8°C
RID/ADR certification :
UN 3462 6.1 / PG 2
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Alternative Distributors of [Cytochalasin H]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

ABCR GmbH & Co. KG | Cfm Oskar Tropitzsch GmbH | Jinan Haohua Industry Co., Ltd. | Clearsynth Canada INC.

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