Chemical-Suppliers Chemical-Suppliers

Compound E

×
Formula: C27H24F2N4O3
CAS: 209986-17-4
search Element: compound
Page Content Identification Properties Suppliers Prices & Availability Get Quick Quote ☰

Identification

Structural Formula
Compound E
CAS:
209986-17-4
EINECS:
Molecular Formula:
C27H24F2N4O3
MDL:
MFCD04974531
SMILES:
C[C@@H](C(=O)N[C@@H]1C(=O)N(C2=CC=CC=C2C(=N1)C3=CC=CC=C3)C)NC(=O)CC4=CC(=CC(=C4)F)F
Synonym:


Description

Compound E is a cell permeable non-competitve inhibitor of γ-secretase. Studies indicate that γ-secretase is a multifunctional transmembrane protein complex that enzymatically catalyzes the cleavage of single-pass transmembrane proteins. One of the most common substrates for this enzyme is amyloid precursor protein. Once cleaved this protein produces amyloid plaques in brain tissue often seen in Alzheimer's disease. Thus Compound E is a useful research tool in Alzheimer's disease.


Suppliers

Aea.ltd
A140280
+
Santa Cruz Biotechnology, Inc.
221433
Get Quick Quote

CAS equal suppliers

?-Secretase Inhibitor XXI
Alpha Biopharmaceuticals Co., Ltd.
AB25507650
γ-Secretase Inhibitor XXI
ShangHai Biochempartner Co., Ltd.
BCP02178
γ-Secretase Inhibitor XXI
Excenen Pharmatech Co., Ltd.
EN-0730
N-[(1S)-2-[[(3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide
Leap Chem Co., Ltd
LC46170138510

Prices & Availability




Data is processed


x

Properties for Compound E

Molecular Weight:
490.50 g·mol−1
Density:
1.31 g/cm3 (Predicted)
Melting point:
322.17° C (Predicted)
Boiling point:
778.56° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (10 mg/ml).
x

Safety & Transport Information

coming up soon
x

Alternative Distributors of [Compound E]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
x

Downloads

Mol File:
-/-
MSDS:
-/-




View related products













▲
▲