Sp-cAMPS | CAS 93602-66-5 | Chemical-Suppliers

Element: camps

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C-S » Chemicals » camps-PX81289

Identification

Sp-cAMPS

CAS:

93602-66-5

EINECS:

Molecular Formula:

C₁₀H₁₁N₅O₅PS.C₆H₁₆N

MDL:

MFCD01459901

SMILES:

C1(=NC=NC2=C1N=C[N]2C3OC4C(C3O[H])O[P](OC4)(=O)[S-])N([H])[H].[N+](CC)(CC)([H])CC

Synonym:

Description

Sp-cAMPS, a stimulatory diastereoisomer of adenosine 3',5'-(cyclic)phosphorothioate, has been shown to contain an axial exocyclic sulphur atom. Experiments have noted that this agent binds to holoenzymes, releases its catalytic subunit and activates phosphotransferase and cAMP-dependent protein kinase activity. Additionally, Sp-cAMPS has demonstrated the ability to mimick glucagon-stimulated increases in the level of Ca²⁺ in hepatocytes.